Zhang, TianArmstrong, Andrew J2015-11-202015-10-151078-0432https://hdl.handle.net/10161/10916Notch signaling is implicated in prostate cancer progression and docetaxel resistance. Cui and colleagues describe the additive efficacy and mechanisms of a γ-secretase inhibitor, PF-03084014, and docetaxel in preclinical models of prostate cancer, suggesting the need for further clinical development of Notch pathway modulators in men with metastatic prostate cancer.Amyloid Precursor Protein SecretasesAnimalsAntineoplastic Combined Chemotherapy ProtocolsHumansMaleProstatic NeoplasmsJournal article