Steelman, Zachary AHo, Derek SChu, Kengyeh KWax, Adam2020-12-202020-12-202019-042334-25362334-2536https://hdl.handle.net/10161/21926Light scattering has become a common biomedical research tool, enabling diagnostic sensitivity to myriad tissue alterations associated with disease. Light-tissue interactions are particularly attractive for diagnostics due to the variety of contrast mechanisms that can be used, including spectral, angle-resolved, and Fourier-domain detection. Photonic diagnostic tools offer further benefit in that they are non-ionizing, non-invasive, and give real-time feedback. In this review, we summarize recent innovations in light scattering technologies, with a focus on clinical achievements over the previous ten years.Science & TechnologyPhysical SciencesOpticsOPTICAL COHERENCE TOMOGRAPHYSPATIAL-FREQUENCY DOMAINDIFFUSE-REFLECTANCE SPECTROSCOPYBIOLOGICAL TISSUENUCLEAR MORPHOLOGYREFRACTIVE-INDEXCELL-NUCLEIIN-VIVOINTERFEROMETRY MEASUREMENTSQUANTITATIVE-ANALYSISJournal article2020-12-20