Reynolds, Staci SueSova, ChrisMcNalty, BridgetLambert, SuzanneGranger, Bradi2023-03-302023-03-302019-041057-36311550-5065https://hdl.handle.net/10161/26931<h4>Background</h4>Evidence supports daily bathing using chlorhexidine gluconate (CHG) cloths to decrease preventable hospital-acquired central line-associated bloodstream infections (CLABSIs). However, implementation of this practice is inconsistent. Using multifaceted strategies to promote implementation is supported in the literature, yet there is a gap in knowing which strategies are most successful.<h4>Purpose</h4>Using the Grol and Wensing Model of Implementation as a guide, the purpose of this study was to determine whether using tailored, multifaceted strategies would improve implementation of daily CHG bathing and decrease CLABSIs in a large neuro ICU.<h4>Methods</h4>An observational pre-/postdesign was used.<h4>Results</h4>Following implementation, infection rates decreased (P = .031). Statistically significant improvements were also seen across all process measures: bathing documentation, nursing knowledge, and perceived importance of CHG bathing.<h4>Conclusions</h4>This study assists in closing the research-practice gap by using tailored, multifaceted implementation strategies to increase use of evidence-based nursing care for infection prevention practices.HumansCross InfectionChlorhexidineAnti-Infective Agents, LocalCatheterization, Central VenousBathsNeurologyIntensive Care UnitsEvidence-Based PracticeCatheter-Related InfectionsCritical Care NursingImplementation ScienceJournal article2023-03-30