Brown, MAZhang, LLevering, VWWu, JHSatterwhite, LLBrian, LFreedman, NJTruskey, GA2024-10-012024-10-012010-111524-46361524-4636https://hdl.handle.net/10161/31545OBJECTIVE: To accelerate vein graft reendothelialization and reduce vein graft thrombosis by infusing human umbilical cord blood-derived endothelial cells (hCB-ECs) because loss of endothelium contributes to vein graft thrombosis and neointimal hyperplasia. RESULTS: Under steady flow conditions in vitro, hCB-ECs adhered to smooth muscle cells 2.5 to 13 times more than ECs derived from peripheral blood or human aorta (Phttps://creativecommons.org/licenses/by-nc/4.0Animals Blood Vessel Prosthesis CellsCultured Endothelial Cells EndotheliumVascular Fetal Blood Graft OcclusionVascular Humans Mice Postoperative Complications Thrombosis Veins Wound Healing cytology physiology physiology* physiopathology prevention & control* surgery*Human umbilical cord blood-derived endothelial cells reendothelialize vein grafts and prevent thrombosis.Journal article