Wells, CarrowLiang, YiPulliam, Thomas LLin, ChenchuAwad, DominikEduful, BenjaminO'Byrne, SeanHossain, Mohammad AnwarCatta-Preta, Carolina Moura CostaRamos, Priscila ZonziniGileadi, OpherGileadi, CarinaCouñago, Rafael MStork, BrittanyLangendorf, Christopher GNay, KevinOakhill, Jonathan SMukherjee, DebaratiRacioppi, LuigiMeans, Anthony RYork, BrianMcDonnell, Donald PScott, John WFrigo, Daniel EDrewry, David H2023-03-012023-03-012023-012073-44092073-4409https://hdl.handle.net/10161/26665The serine/threonine protein kinase calcium/calmodulin-dependent protein kinase kinase 2 (CAMKK2) plays critical roles in a range of biological processes. Despite its importance, only a handful of inhibitors of CAMKK2 have been disclosed. Having a selective small molecule tool to interrogate this kinase will help demonstrate that CAMKK2 inhibition can be therapeutically beneficial. Herein, we disclose SGC-CAMKK2-1, a selective chemical probe that targets CAMKK2.CAMKK2NanoBRETchemical probekinasekinase selectivityJournal article2023-03-01