Browsing by Author "Agarwal, Richa"
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Item Open Access A Case of Rare Inherited Restrictive Cardiomyopathy With Severe Biatrial Enlargement.(JACC. Case reports, 2019-12) Nafissi, Navid A; Fudim, Marat; Milano, Carmelo A; Rosenberg, Paul B; DeVore, Adam D; Agarwal, RichaWe describe a case of inherited restrictive cardiomyopathy in a patient presenting with severe biatrial enlargement. We review the evaluation and management of restrictive cardiomyopathy with a focus on genetic etiologies. (Level of Difficulty: Intermediate.).Item Open Access Challenges in Pulmonary Hypertension: Controversies in Treating the Tip of the Iceberg. A Joint National Institutes of Health Clinical Center and Pulmonary Hypertension Association Symposium Report(American Journal of Respiratory and Critical Care Medicine, 2018-07-15) Elinoff, Jason M; Agarwal, Richa; Barnett, Christopher F; Benza, Raymond L; Cuttica, Michael J; Gharib, Ahmed M; Gray, Michael P; Hassoun, Paul M; Hemnes, Anna R; Humbert, Marc; Kolb, Todd M; Lahm, Tim; Leopold, Jane A; Mathai, Stephen C; McLaughlin, Vallerie V; Preston, Ioana R; Rosenzweig, Erika B; Shlobin, Oksana A; Steen, Virginia D; Zamanian, Roham T; Solomon, Michael AItem Open Access Current therapeutics and practical management strategies for pulmonary arterial hypertension(American Heart Journal, 2011-08) Agarwal, Richa; Gomberg-Maitland, MardiItem Open Access Hemodynamic Response to Treatment of Iron Deficiency Anemia in Pulmonary Arterial Hypertension: Longitudinal Insights from an Implantable Hemodynamic Monitor(Pulmonary Circulation, 2016-12) Mehmood, Muddassir; Agarwal, Richa; Raina, Amresh; Correa‐Jaque, Priscilla; Benza, Raymond LDespite new therapeutic options, pulmonary arterial hypertension (PAH) remains a progressive disease associated with substantial morbidity and mortality. As such, additional strategies for monitoring and adjunctive management of this disease are important. A 59-year-old woman with scleroderma-associated PAH received an implantable hemodynamic monitor (IHM) as part of a research protocol at our institution. Pulmonary artery pressures, heart rate, and cardiac output (sensor-based algorithm) were measured on a daily basis, and parameters of right ventricular (RV) performance and afterload were calculated. At the time of IHM implant, the patient had functional class III symptoms, was receiving triple-drug therapy, and had normal hemoglobin levels. Four months after implant, and with further optimization of prostacyclin therapy, she had improvement in her symptoms. However, shortly thereafter, while the patient was receiving stable drug therapy, her case regressed with worsening symptoms, and the patient received a new diagnosis of iron deficiency anemia. Oral iron supplementation resulted in normalization of hemoglobin levels and improvement in the patient's iron profile. A gradual and sustained reduction in pulmonary pressures was noted after initiation of oral iron accompanied by increased RV performance and favorable reduction in RV afterload. The patient had significant symptomatic improvement. Iron deficiency is an underappreciated yet easily treatable risk factor in PAH. Use of IHM in this case longitudinally illustrates the optimization of pulmonary hemodynamics and RV afterload in tandem with clinical improvement achieved by a simple therapy.Item Open Access High Transpulmonary Artery Gradient Obtained at the Time of Left Ventricular Assist Device Implantation Negatively Affects Survival After Cardiac Transplantation(Journal of Cardiac Failure, 2019-10) Uriel, Nir; Imamura, Teruhiko; Sayer, Gabriel; Agarwal, Richa; Sims, Daniel B; Takayama, Hiroo; John, Ranjit; Pagani, Francis D; Naka, Yoshifumi; Sundareswaran, Kartik S; Farrar, David J; Jorde, Ulrich PItem Open Access Macitentan (Opsumit) for the treatment of pulmonary arterial hypertension(Expert Review of Clinical Pharmacology, 2014-07) Clarke, Megan; Walter, Claire; Agarwal, Richa; Kanwar, Manreet; Benza, Raymond LItem Open Access Management of Pulmonary Hypertension due to Heart Failure with Preserved Ejection Fraction(Current Hypertension Reports, 2014-12) Kanwar, Manreet; Tedford, Ryan J; Agarwal, Richa; Clarke, Megan M; Walter, Claire; Sokos, George; Murali, Srinivas; Benza, Raymond LItem Open Access Orthostatic Syncope from Compromised Flow after Heartware HVAD by Lateral Thoracotomy: Potential Role of Dynamic Echocardiographic Testing for Cannula Assessment(CASE, 2017-04) Thangavel, Sarumathi; Raina, Amresh; Agarwal, RichaItem Open Access Phosphodiesterase-5 Inhibitors and Outcomes During Left Ventricular Assist Device Support: A Systematic Review and Meta-Analysis(Journal of Cardiac Failure, 2020-12) Kittipibul, Veraprapas; Blumer, Vanessa; Angsubhakorn, Natthapon; Hernandez, Gabriel A; Chaparro, Sandra; Tedford, Ryan J; Agarwal, RichaItem Open Access Physiologic Markers of Exercise as a Potential Screening Tool for the Detection of Pulmonary Hypertension(Chest, 2016-02) Agarwal, Richa; Gomberg-Maitland, MardiItem Open Access Prognostication in Pulmonary Arterial Hypertension(Heart Failure Clinics, 2012-07) Agarwal, Richa; Gomberg-Maitland, MardiItem Open Access Risk assessment in pulmonary hypertension associated with heart failure and preserved ejection fraction(The Journal of Heart and Lung Transplantation, 2012-05) Agarwal, Richa; Shah, Sanjiv J; Foreman, Aimee J; Glassner, Cherylanne; Bartolome, Sonja D; Safdar, Zeenat; Coslet, Sandra L; Anderson, Allen S; Gomberg-Maitland, MardiItem Open Access Role of Phosphodiesterase-5 Inhibitors in Heart Failure: Emerging Data and Concepts(Current Heart Failure Reports, 2013-03) Kanwar, Manreet; Agarwal, Richa; Barnes, Megan; Coons, James; Raina, Amresh; Sokos, George; Murali, Srinivas; Benza, Raymond LItem Open Access Significance of Residual Mitral Regurgitation After Continuous Flow Left Ventricular Assist Device Implantation(JACC: Heart Failure, 2017-02) Kassis, Hayah; Cherukuri, Krishna; Agarwal, Richa; Kanwar, Manreet; Elapavaluru, Subbarao; Sokos, George G; Moraca, Robert J; Bailey, Stephen H; Murali, Srinivas; Benza, Raymond L; Raina, AmreshItem Open Access Treadmill testing improves survival prediction models in pulmonary arterial hypertension(American Heart Journal, 2011-12) Hsu, Chih-Hsin; Glassner, Cherylanne; Foreman, Aimee J; Agarwal, Richa; Benza, Raymond J; Frantz, Robert P; Gomberg-Maitland, Mardi