Browsing by Author "Fu, Qiang"

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    Contemporary radical prostatectomy.
    (Prostate Cancer, 2011) Fu, Qiang; Moul, Judd W; Sun, Leon
    Purpose. Patients diagnosed with clinically localized prostate cancer have more surgical treatment options than in the past. This paper focuses on the procedures' oncological or functional outcomes and perioperative morbidities of radical retropubic prostatectomy, radical perineal prostatectomy, and robotic-assisted laparoscopic radical prostatectomy. Materials and Methods. A MEDLINE/PubMed search of the literature on radical prostatectomy and other new management options was performed. Results. Compared to the open procedures, robotic-assisted radical prostatectomy has no confirmed significant difference in most literatures besides less blood loss and blood transfusion. Nerve sparing is a safe means of preserving potency on well-selected patients undergoing radical prostatectomy. Positive surgical margin rates of radical prostatectomy affect the recurrence and survival of prostate cancer. The urinary and sexual function outcomes have been vastly improved. Neoadjuvant treatment only affects the rate of positive surgical margin. Adjuvant therapy can delay and reduce the risk of recurrence and improve the survival of the high risk prostate cancer. Conclusions. For the majority of patients with organ-confined prostate cancer, radical prostatectomy remains a most effective approach. Radical perineal prostatectomy remains a viable approach for patients with morbid obesity, prior pelvic surgery, or prior pelvic radiation. Robot-assisted laparoscopic prostatectomy (RALP) has become popular among surgeons but has not yet become the firmly established standard of care. Long-term data have confirmed the efficacy of radical retropubic prostatectomy with disease control rates and cancer-specific survival rates.
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    Psychiatric correlates of snuff and chewing tobacco use.
    (PLoS One, 2014) Fu, Qiang; Vaughn, Michael G; Wu, Li-Tzy; Heath, Andrew C
    Compared to the association between cigarette smoking and psychiatric disorders, relatively little is known about the relationship between smokeless tobacco use and psychiatric disorders. To identify the psychiatric correlates of smokeless tobacco use, the analysis used a national representative sample from the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC) wave 1. Smokeless tobacco use was classified as exclusive snuff use, exclusive chewing tobacco, and dual use of both snuff and chewing tobacco at some time in the smokeless tobacco user's life. Lifetime psychiatric disorders were obtained via structured diagnostic interviews. The results show that the prevalence of lifetime exclusive snuff use, exclusive chewing tobacco, and dual use of both snuff and chewing tobacco was 2.16%, 2.52%, and 2.79%, respectively. After controlling for sociodemographic variables and cigarette smoking, the odds of exclusive chewing tobacco in persons with panic disorder and specific phobia were 1.53 and 1.41 times the odds in persons without those disorders, respectively. The odds of exclusive snuff use, exclusive chewing tobacco, and dual use of both products for individuals with alcohol use disorder were 1.97, 2.01, and 2.99 times the odds for those without alcohol use disorder, respectively. Respondents with cannabis use disorder were 1.44 times more likely to use snuff exclusively than those without cannabis use disorder. Respondents with inhalant/solvent use disorder were associated with 3.33 times the odds of exclusive chewing tobacco. In conclusion, this study highlights the specific links of anxiety disorder, alcohol, cannabis, and inhalant/solvent use disorders with different types of smokeless tobacco use.
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    Risk profiles among adolescent nonmedical opioid users in the United States.
    (Addictive behaviors, 2012-08) Vaughn, Michael G; Fu, Qiang; Perron, Brian E; Wu, Li-Tzy
    Although prior research has provided data on nonmedical use of opioids in adolescents, studies examining the heterogeneity of risk are limited. The present study extends prior research by deepening the understanding of adolescent nonmedical opioid use by specifying empirically meaningful profiles of risk. Using data on adolescent non-medical opioid users (N=1783) from the 2008 US National Survey on Drug Use and Health (NSDUH), latent class analysis and multinomial logistic regression were employed to identify latent classes and determine the effects of covariates on class membership. Four latent classes provided the best fit to the data. Classes consisted of a low risk class (33.7%), a high delinquency/low substance use class (17.8%), a high substance use/low delinquency class (34.2%), and finally a high risk class (14.3%) characterized by high levels of both substance use and delinquent behavior. Study findings advance the understanding of adolescent nonmedical opioid use by specifying distinct latent classes. Results suggest that intervention efforts can fruitfully target a number of risk domains especially programs that enhance effective parenting and supervision.
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    The Global Epidemic of Childhood Obesity and Its Non-medical Costs
    (2015) Fu, Qiang

    This dissertation consists of three parts of empirical analyses investigating temporal patterns and consequences of (childhood) overweight and obesity, mainly in the United States and the People's Republic of China. Based on the China Health and Nutrition Survey, the first part conducts hierarchical age-period-cohort analyses of childhood overweight in China and finds a strong cohort effect driving the overweight epidemic. Results from the growth-curve models show that childhood overweight and underweight are related such that certain socio-economic groups with higher levels of childhood overweight also exhibit lower levels of childhood underweight. The second part situates the discussion on childhood obesity in a broader context. It compares temporal patterns of childhood overweight in China with these of adulthood overweight and finds that the salient cohort component is absent in rising adulthood overweight, which is dominated by strong period effects. A positive association between human development index and overweight/obesity prevalence across countries is also documented. Using multiple waves of survey data from the National Longitudinal Study of Adolescent Health, the third part analyzes the (latent) trajectory of childhood overweight/obesity in the United States. It finds that individuals with obesity growth trajectories are less likely to avoid mental depression, tend to have higher levels of neuroticism and lower levels of agreeableness/conscientiousness, and show less delinquent behaviors.