Browsing by Author "Herzog, DP"
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Item Open Access Ergodicity and Lyapunov functions for Langevin dynamics with singular potentials(2017-11-30) Herzog, DP; Mattingly, JCWe study Langevin dynamics of $N$ particles on $R^d$ interacting through a singular repulsive potential, e.g.~the well-known Lennard-Jones type, and show that the system converges to the unique invariant Gibbs measure exponentially fast in a weighted total variation distance. The proof of the main result relies on an explicit construction of a Lyapunov function. In contrast to previous results for such systems, our result implies geometric convergence to equilibrium starting from an essentially optimal family of initial distributions.Item Open Access Gibbsian dynamics and the generalized Langevin equationHerzog, DP; Mattingly, JC; Nguyen, HDWe study the statistically invariant structures of the nonlinear generalized Langevin equation (GLE) with a power-law memory kernel. For a broad class of memory kernels, including those in the subdiffusive regime, we construct solutions of the GLE using a Gibbsian framework, which does not rely on existing Markovian approximations. Moreover, we provide conditions on the decay of the memory to ensure uniqueness of statistically steady states, generalizing previous known results for the GLE under particular kernels as a sum of exponentials.Item Open Access Impact of coverage-dependent marginal costs on optimal HPV vaccination strategies.(Epidemics, 2015-06) Ryser, MD; McGoff, K; Herzog, DP; Sivakoff, DJ; Myers, ERThe effectiveness of vaccinating males against the human papillomavirus (HPV) remains a controversial subject. Many existing studies conclude that increasing female coverage is more effective than diverting resources into male vaccination. Recently, several empirical studies on HPV immunization have been published, providing evidence of the fact that marginal vaccination costs increase with coverage. In this study, we use a stochastic agent-based modeling framework to revisit the male vaccination debate in light of these new findings. Within this framework, we assess the impact of coverage-dependent marginal costs of vaccine distribution on optimal immunization strategies against HPV. Focusing on the two scenarios of ongoing and new vaccination programs, we analyze different resource allocation policies and their effects on overall disease burden. Our results suggest that if the costs associated with vaccinating males are relatively close to those associated with vaccinating females, then coverage-dependent, increasing marginal costs may favor vaccination strategies that entail immunization of both genders. In particular, this study emphasizes the necessity for further empirical research on the nature of coverage-dependent vaccination costs.Item Open Access Noise-induced stabilization of planar flows I(Electronic Journal of Probability, 2015-10-22) Herzog, DP; Mattingly, JC© 2015 University of Washington. All rights reserved.We show that the complex-valued ODE (n ≥ 1, an+1 6≠ 0): ź = an+1zn+1 + anzn +1zn + a0; which necessarily has trajectories along which the dynamics blows up in finite time, can be stabilized by the addition of an arbitrarily small elliptic, additive Brownian stochastic term. We also show that the stochastic perturbation has a unique invariant probability measure which is heavy-tailed yet is uniformly, exponentially attracting. The methods turn on the construction of Lyapunov functions. The techniques used in the construction are general and can likely be used in other settings where a Lyapunov function is needed. This is a two-part paper. This paper, Part I, focuses on general Lyapunov methods as applied to a special, simplified version of the problem. Part II [11] extends the main results to the general setting.Item Open Access Scaling and Saturation in Infinite-Dimensional Control Problems with Applications to Stochastic Partial Differential Equations(2017-07-27) Glatt-Holtz, NE; Herzog, DP; Mattingly, JCWe establish the dual notions of scaling and saturation from geometric control theory in an infinite-dimensional setting. This generalization is applied to the low-mode control problem in a number of concrete nonlinear partial differential equations. We also develop applications concerning associated classes of stochastic partial differential equations (SPDEs). In particular, we study the support properties of probability laws corresponding to these SPDEs as well as provide applications concerning the ergodic and mixing properties of invariant measures for these stochastic systems.