Browsing by Author "Lavadi, Raj Swaroop"

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    ItemOpen Access
    Cervical spondylotic myelopathy and driving abilities: defining the prevalence and long-term postoperative outcomes using the Quality Outcomes Database.
    (Journal of neurosurgery. Spine, 2024-02) Agarwal, Nitin; Johnson, Sarah E; Bydon, Mohamad; Bisson, Erica F; Chan, Andrew K; Shabani, Saman; Letchuman, Vijay; Michalopoulos, Giorgos D; Lu, Daniel C; Wang, Michael Y; Lavadi, Raj Swaroop; Haid, Regis W; Knightly, John J; Sherrod, Brandon A; Gottfried, Oren N; Shaffrey, Christopher I; Goldberg, Jacob L; Virk, Michael S; Hussain, Ibrahim; Glassman, Steven D; Shaffrey, Mark E; Park, Paul; Foley, Kevin T; Pennicooke, Brenton; Coric, Domagoj; Slotkin, Jonathan R; Upadhyaya, Cheerag; Potts, Eric A; Tumialán, Luis M; Chou, Dean; Fu, Kai-Ming G; Asher, Anthony L; Mummaneni, Praveen V

    Objective

    Cervical spondylotic myelopathy (CSM) can cause significant difficulty with driving and a subsequent reduction in an individual's quality of life due to neurological deterioration. The positive impact of surgery on postoperative patient-reported driving capabilities has been seldom explored.

    Methods

    The CSM module of the Quality Outcomes Database was utilized. Patient-reported driving ability was assessed via the driving section of the Neck Disability Index (NDI) questionnaire. This is an ordinal scale in which 0 represents the absence of symptoms while driving and 5 represents a complete inability to drive due to symptoms. Patients were considered to have an impairment in their driving ability if they reported an NDI driving score of 3 or higher (signifying impairment in driving duration due to symptoms). Multivariable logistic regression models were fitted to evaluate mediators of baseline impairment and improvement at 24 months after surgery, which was defined as an NDI driving score < 3.

    Results

    A total of 1128 patients who underwent surgical intervention for CSM were included, of whom 354 (31.4%) had baseline driving impairment due to CSM. Moderate (OR 2.3) and severe (OR 6.3) neck pain, severe arm pain (OR 1.6), mild-moderate (OR 2.1) and severe (OR 2.5) impairment in hand/arm dexterity, severe impairment in leg use/walking (OR 1.9), and severe impairment of urinary function (OR 1.8) were associated with impaired driving ability at baseline. Of the 291 patients with baseline impairment and available 24-month follow-up data, 209 (71.8%) reported postoperative improvement in their driving ability. This improvement seemed to be mediated particularly through the achievement of the minimal clinically important difference (MCID) in neck pain and improvement in leg function/walking. Patients with improved driving at 24 months noted higher postoperative satisfaction (88.5% vs 62.2%, p < 0.01) and were more likely to achieve a clinically significant improvement in their quality of life (50.7% vs 37.8%, p < 0.01).

    Conclusions

    Nearly one-third of patients with CSM report impaired driving ability at presentation. Seventy-two percent of these patients reported improvements in their driving ability within 24 months of surgery. Surgical management of CSM can significantly improve patients' driving abilities at 24 months and hence patients' quality of life.
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    Impact of Educational Background on Preoperative Disease Severity and Postoperative Outcomes Among Patients With Cervical Spondylotic Myelopathy.
    (Clinical spine surgery, 2023-12) Agarwal, Nitin; DiGiorgio, Anthony; Michalopoulos, Giorgos D; Letchuman, Vijay; Chan, Andrew K; Shabani, Saman; Lavadi, Raj Swaroop; Lu, Daniel C; Wang, Michael Y; Haid, Regis W; Knightly, John J; Sherrod, Brandon A; Gottfried, Oren N; Shaffrey, Christopher I; Goldberg, Jacob L; Virk, Michael S; Hussain, Ibrahim; Glassman, Steven D; Shaffrey, Mark E; Park, Paul; Foley, Kevin T; Pennicooke, Brenton; Coric, Domagoj; Upadhyaya, Cheerag; Potts, Eric A; Tumialán, Luis M; Fu, Kai-Ming G; Asher, Anthony L; Bisson, Erica F; Chou, Dean; Bydon, Mohamad; Mummaneni, Praveen V

    Study design

    Retrospective review of a prospectively maintained database.

    Objective

    Assess differences in preoperative status and postoperative outcomes among patients of different educational backgrounds undergoing surgical management of cervical spondylotic myelopathy (CSM).

    Summary of background data

    Patient education level (EL) has been suggested to correlate with health literacy, disease perception, socioeconomic status (SES), and access to health care.

    Methods

    The CSM data set of the Quality Outcomes Database (QOD) was queried for patients undergoing surgical management of CSM. EL was grouped as high school or below, graduate-level, and postgraduate level. The association of EL with baseline disease severity (per patient-reported outcome measures), symptoms >3 or ≤3 months, and 24-month patient-reported outcome measures were evaluated.

    Results

    Among 1141 patients with CSM, 509 (44.6%) had an EL of high school or below, 471 (41.3%) had a graduate degree, and 161 (14.1%) had obtained postgraduate education. Lower EL was statistically significantly associated with symptom duration of >3 months (odds ratio=1.68), higher arm pain numeric rating scale (NRS) (coefficient=0.5), and higher neck pain NRS (coefficient=0.79). Patients with postgraduate education had statistically significantly lower Neck Disability Index (NDI) scores (coefficient=-7.17), lower arm pain scores (coefficient=-1), and higher quality-adjusted life-years (QALY) scores (coefficient=0.06). Twenty-four months after surgery, patients of lower EL had higher NDI scores, higher pain NRS scores, and lower QALY scores (P<0.05 in all analyses).

    Conclusions

    Among patients undergoing surgical management for CSM, those reporting a lower educational level tended to present with longer symptom duration, more disease-inflicted disability and pain, and lower QALY scores. As such, patients of a lower EL are a potentially vulnerable subpopulation, and their health literacy and access to care should be prioritized.
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    ItemOpen Access
    What is the effect of preoperative depression on outcomes after minimally invasive surgery for adult spinal deformity? A prospective cohort analysis
    (JOURNAL OF NEUROSURGERY-SPINE, 2024) Agarwal, Nitin; Letchuman, Vijay; Lavadi, Raj Swaroop; Le, Vivian P; Aabedi, Alexander A; Shabani, Saman; Chan, Andrew K; Park, Paul; Uribe, Juan S; Turner, Jay D; Eastlack, Robert K; Fessler, Richard G; Fu, Kai-Ming; Wang, Michael Y; Kanter, Adam S; Okonkwo, David O; Nunley, Pierce D; Anand, Neel; Mundis Jr, Gregory M; Passias, Peter G; Bess, Shay; Shaffrey, Christopher I; Chou, Dean; Mummaneni, Praveen V
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    ItemOpen Access
    What is the effect of preoperative depression on outcomes after minimally invasive surgery for adult spinal deformity? A prospective cohort analysis.
    (J Neurosurg Spine, 2024-02-16) Agarwal, Nitin; Letchuman, Vijay; Lavadi, Raj Swaroop; Le, Vivian P; Aabedi, Alexander A; Shabani, Saman; Chan, Andrew K; Park, Paul; Uribe, Juan S; Turner, Jay D; Eastlack, Robert K; Fessler, Richard G; Fu, Kai-Ming; Wang, Michael Y; Kanter, Adam S; Okonkwo, David O; Nunley, Pierce D; Anand, Neel; Mundis, Gregory M; Passias, Peter G; Bess, Shay; Shaffrey, Christopher I; Chou, Dean; Mummaneni, Praveen V
    OBJECTIVE: Depression has been implicated with worse immediate postoperative outcomes in adult spinal deformity (ASD) correction, yet the specific impact of depression on those patients undergoing minimally invasive surgery (MIS) requires further clarity. This study aimed to evaluate the role of depression in the recovery of patients with ASD after undergoing MIS. METHODS: Patients who underwent MIS for ASD with a minimum postoperative follow-up of 1 year were included from a prospectively collected, multicenter registry. Two cohorts of patients were identified that consisted of either those affirming or denying depression on preoperative assessment. The patient-reported outcome measures (PROMs) compared included scores on the Oswestry Disability Index (ODI), numeric rating scale (NRS) for back and leg pain, Scoliosis Research Society Outcomes Questionnaire (SRS-22), SF-36 physical component summary, SF-36 mental component summary (MCS), EQ-5D, and EQ-5D visual analog scale. RESULTS: Twenty-seven of 147 (18.4%) patients screened positive for preoperative depression. The nondepressed cohort had an average of 4.83 levels fused, and the depressed cohort had 5.56 levels fused per patient (p = 0.267). At 1-year follow-up, 10 patients still reported depression, representing a 63% decrease. Postoperatively, both cohorts demonstrated improvement in their PROMs; however, at 1-year follow-up, those without depression had statistically better outcomes based on the EQ-5D, MCS, and SRS-22 scores (p < 0.05). Patients with depression continued to experience higher NRS leg scores at 1-year follow-up (3.63 vs 2.22, p = 0.018). After controlling for covariates, the authors found that depression significantly impacted only 1-year follow-up MCS scores (β = 8.490, p < 0.05). CONCLUSIONS: Depressed and nondepressed patients reported similar improvements after MIS surgery, except MCS scores were more likely to improve in nondepressed patients.