Browsing by Author "Newman, Michael"
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Item Open Access Fault-tolerant control of an error-corrected qubit.(Nature, 2021-10) Egan, Laird; Debroy, Dripto M; Noel, Crystal; Risinger, Andrew; Zhu, Daiwei; Biswas, Debopriyo; Newman, Michael; Li, Muyuan; Brown, Kenneth R; Cetina, Marko; Monroe, ChristopherQuantum error correction protects fragile quantum information by encoding it into a larger quantum system1,2. These extra degrees of freedom enable the detection and correction of errors, but also increase the control complexity of the encoded logical qubit. Fault-tolerant circuits contain the spread of errors while controlling the logical qubit, and are essential for realizing error suppression in practice3-6. Although fault-tolerant design works in principle, it has not previously been demonstrated in an error-corrected physical system with native noise characteristics. Here we experimentally demonstrate fault-tolerant circuits for the preparation, measurement, rotation and stabilizer measurement of a Bacon-Shor logical qubit using 13 trapped ion qubits. When we compare these fault-tolerant protocols to non-fault-tolerant protocols, we see significant reductions in the error rates of the logical primitives in the presence of noise. The result of fault-tolerant design is an average state preparation and measurement error of 0.6 per cent and a Clifford gate error of 0.3 per cent after offline error correction. In addition, we prepare magic states with fidelities that exceed the distillation threshold7, demonstrating all of the key single-qubit ingredients required for universal fault-tolerant control. These results demonstrate that fault-tolerant circuits enable highly accurate logical primitives in current quantum systems. With improved two-qubit gates and the use of intermediate measurements, a stabilized logical qubit can be achieved.Item Open Access Stabilizer Slicing: Coherent Error Cancellations in Low-Density Parity-Check Stabilizer Codes.(Physical review letters, 2018-12) Debroy, Dripto M; Li, Muyuan; Newman, Michael; Brown, Kenneth RCoherent errors are a dominant noise process in many quantum computing architectures. Unlike stochastic errors, these errors can combine constructively and grow into highly detrimental overrotations. To combat this, we introduce a simple technique for suppressing systematic coherent errors in low-density parity-check stabilizer codes, which we call stabilizer slicing. The essential idea is to slice low-weight stabilizers into two equally weighted Pauli operators and then apply them by rotating in opposite directions, causing their overrotations to interfere destructively on the logical subspace. With access to native gates generated by three-body Hamiltonians, we can completely eliminate purely coherent overrotation errors, and for overrotation noise of 0.99 unitarity we achieve a 135-fold improvement in the logical error rate of surface-17. For more conventional two-body ion trap gates, we observe an 89-fold improvement for Bacon-Shor-13 with purely coherent errors which should be testable in near-term fault-tolerance experiments. This second scheme takes advantage of the prepared gauge degrees of freedom, and to our knowledge is the first example in which the state of the gauge directly affects the robustness of a code's memory. This Letter demonstrates that coherent noise is preferable to stochastic noise within certain code and gate implementations when the coherence is utilized effectively.Item Open Access The first 20 months of the COVID-19 pandemic: Mortality, intubation and ICU rates among 104,590 patients hospitalized at 21 United States health systems.(PloS one, 2022-01) Fiore, Michael C; Smith, Stevens S; Adsit, Robert T; Bolt, Daniel M; Conner, Karen L; Bernstein, Steven L; Eng, Oliver D; Lazuk, David; Gonzalez, Alec; Jorenby, Douglas E; D'Angelo, Heather; Kirsch, Julie A; Williams, Brian; Nolan, Margaret B; Hayes-Birchler, Todd; Kent, Sean; Kim, Hanna; Piasecki, Thomas M; Slutske, Wendy S; Lubanski, Stan; Yu, Menggang; Suk, Youmi; Cai, Yuxin; Kashyap, Nitu; Mathew, Jomol P; McMahan, Gabriel; Rolland, Betsy; Tindle, Hilary A; Warren, Graham W; An, Lawrence C; Boyd, Andrew D; Brunzell, Darlene H; Carrillo, Victor; Chen, Li-Shiun; Davis, James M; Dilip, Deepika; Ellerbeck, Edward F; Iturrate, Eduardo; Jose, Thulasee; Khanna, Niharika; King, Andrea; Klass, Elizabeth; Newman, Michael; Shoenbill, Kimberly A; Tong, Elisa; Tsoh, Janice Y; Wilson, Karen M; Theobald, Wendy E; Baker, Timothy BMain objective
There is limited information on how patient outcomes have changed during the COVID-19 pandemic. This study characterizes changes in mortality, intubation, and ICU admission rates during the first 20 months of the pandemic.Study design and methods
University of Wisconsin researchers collected and harmonized electronic health record data from 1.1 million COVID-19 patients across 21 United States health systems from February 2020 through September 2021. The analysis comprised data from 104,590 adult hospitalized COVID-19 patients. Inclusion criteria for the analysis were: (1) age 18 years or older; (2) COVID-19 ICD-10 diagnosis during hospitalization and/or a positive COVID-19 PCR test in a 14-day window (+/- 7 days of hospital admission); and (3) health system contact prior to COVID-19 hospitalization. Outcomes assessed were: (1) mortality (primary), (2) endotracheal intubation, and (3) ICU admission.Results and significance
The 104,590 hospitalized participants had a mean age of 61.7 years and were 50.4% female, 24% Black, and 56.8% White. Overall risk-standardized mortality (adjusted for age, sex, race, ethnicity, body mass index, insurance status and medical comorbidities) declined from 16% of hospitalized COVID-19 patients (95% CI: 16% to 17%) early in the pandemic (February-April 2020) to 9% (CI: 9% to 10%) later (July-September 2021). Among subpopulations, males (vs. females), those on Medicare (vs. those on commercial insurance), the severely obese (vs. normal weight), and those aged 60 and older (vs. younger individuals) had especially high mortality rates both early and late in the pandemic. ICU admission and intubation rates also declined across these 20 months.Conclusions
Mortality, intubation, and ICU admission rates improved markedly over the first 20 months of the pandemic among adult hospitalized COVID-19 patients although gains varied by subpopulation. These data provide important information on the course of COVID-19 and identify hospitalized patient groups at heightened risk for negative outcomes.Trial registration
ClinicalTrials.gov Identifier: NCT04506528 (https://clinicaltrials.gov/ct2/show/NCT04506528).