Browsing by Author "Pollock, Nira R"
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Item Open Access The Positive Predictive Value of Lyme Elisa for the Diagnosis of Lyme Disease in Children.(Pediatr Infect Dis J, 2015-11) Lipsett, Susan C; Pollock, Nira R; Branda, John A; Gordon, Caroline D; Gordon, Catherine R; Lantos, Paul M; Nigrovic, Lise EBy using a Lyme enzyme-linked immunosorbent assay (ELISA), we demonstrated that high ELISA index values are strongly predictive of Lyme disease. In children with clinical presentations consistent with Lyme disease, ELISA index values ≥3.0 had a positive predictive value of 99.4% (95% confidence interval: 98.1-99.8%) for Lyme disease, making a supplemental Western immunoblot potentially unnecessary.