Browsing by Author "Wu, X"

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    A framework for integrating the songbird brain.
    (J Comp Physiol A Neuroethol Sens Neural Behav Physiol, 2002-12) Jarvis, ED; Smith, VA; Wada, K; Rivas, MV; McElroy, M; Smulders, TV; Carninci, P; Hayashizaki, Y; Dietrich, F; Wu, X; McConnell, P; Yu, J; Wang, PP; Hartemink, AJ; Lin, S
    Biological systems by default involve complex components with complex relationships. To decipher how biological systems work, we assume that one needs to integrate information over multiple levels of complexity. The songbird vocal communication system is ideal for such integration due to many years of ethological investigation and a discreet dedicated brain network. Here we announce the beginnings of a songbird brain integrative project that involves high-throughput, molecular, anatomical, electrophysiological and behavioral levels of analysis. We first formed a rationale for inclusion of specific biological levels of analysis, then developed high-throughput molecular technologies on songbird brains, developed technologies for combined analysis of electrophysiological activity and gene regulation in awake behaving animals, and developed bioinformatic tools that predict causal interactions within and between biological levels of organization. This integrative brain project is fitting for the interdisciplinary approaches taken in the current songbird issue of the Journal of Comparative Physiology A and is expected to be conducive to deciphering how brains generate and perceive complex behaviors.
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    Correction to: AI is a viable alternative to high throughput screening: a 318-target study (Scientific Reports, (2024), 14, 1, (7526), 10.1038/s41598-024-54655-z)
    (Scientific Reports, 2024-12-01) Giles, E; Heifets, A; Artía, Z; Inde, Z; Liu, Z; Zhang, Z; Wang, Z; Su, Z; Chung, Z; Frangos, ZJ; Li, Y; Yen, Y; Sidorova, YA; Tse-Dinh, YC; He, Y; Tang, Y; Li, Y; Pérez-Pertejo, Y; Gupta, YK; Zhu, Y; Sun, Y; Li, Y; Chen, Y; Aldhamen, YA; Hu, Y; Zhang, YJ; Zhang, X; Yuan, X; Wang, X; Qin, X; Yu, X; Xu, X; Qi, X; Lu, X; Wu, X; Blanchet, X; Foong, WE; Bradshaw, WJ; Gerwick, WH; Kerr, WG; Hahn, WC; Donaldson, WA; Van Voorhis, WC; Zhang, W; Tang, W; Li, W; Houry, WA; Lowther, WT; Clayton, WB; Van Hung Le, V; Ronchi, VP; Woods, VA; Scoffone, VC; Maltarollo, VG; Dolce, V; Maranda, V; Segers, VFM; Namasivayam, V; Gunasekharan, V; Robinson, VL; Banerji, V; Tandon, V; Thai, VC; Pai, VP; Desai, UR; Baumann, U; Chou, TF; Chou, T; O’Mara, TA; Banjo, T; Su, T; Lan, T; Ogunwa, TH; Hermle, T; Corson, TW; O’Meara, TR; Kotzé, TJ; Herdendorf, TJ; Richardson, TI; Kampourakis, T; Gillingwater, TH; Jayasinghe, TD; Teixeira, TR; Ikegami, T; Moreda, TL; Haikarainen, T; Akopian, T; Abaffy, T; Swart, T; Mehlman, T; Teramoto, T; Azeem, SM; Dallman, S; Brady-Kalnay, SM; Sarilla, S; Van Doren, SR; Marx, SO; Olson, SH; Poirier, S; Waggoner, SN
    Correction to: Scientific Reportshttps://doi.org/10.1038/s41598-024-54655-z, published online 02 April 2024 The original version of this Article contained errors. In the original version of this article, Ellie Giles was omitted from the Author list. Additionally, the following Affiliation information has been updated: 1. Affiliation 25 was incorrect. Affiliation 25 ‘Queensland University of Technology, Brisbane, USA.’ now reads, ‘Queensland University of Technology, Brisbane, Australia.’ 2. Marta Giorgis was incorrectly affiliated with the ‘University of Aberdeen, Aberdeen, UK.’ The correct Affiliation is listed below: ‘University of Turin, Turin, Italy.’ 3. Affiliations 52, 125 and 261 were duplicated. As a result, the correct Affiliation for Andrew B. Herr, Benjamin Liou, David A. Hildeman, Joseph J. Maciag, Ying Sun, Durga Krishnamurthy, and Stephen N. Waggoner is: ‘Cincinnati Children’s Hospital Medical Center, Cincinnati, USA.’ Furthermore, an outdated version of Figure 1 was typeset. The original Figure 1 and accompanying legend appear below. (Figure presented.) Pairs of representative compounds extracted from AI patents (right) and corresponding prior patents (left) for clinical-stage programs (CDK792,93, A2Ar-antagonist94,95, MALT196,97, QPCTL98,99, USP1100,101, and 3CLpro102,103). The identical atoms between the chemical structures are highlighted in red. Lastly, The Acknowledgements section contained an error. “See Supplementary section S1.” now reads, “See Supplementary section S2.” The original Article has been corrected.