Browsing by Author "Zeiser, Robert"

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    B-cell targeting in chronic Graft-versus-Host disease.
    (Blood, 2018-02-01) Zeiser, Robert; Sarantopoulos, Stefanie; Blazar, Bruce R
    Over the last decade our understanding of the pathophysiology of chronic graft-versus-host disease (cGVHD) has improved considerably. In this spotlight, we discuss emerging insights into the pathophysiology of cGVHD with a focus on B-cells. First, we summarize supporting evidence derived from mouse and human studies. Next, novel cGVHD therapy approaches that target B-cells will be covered to provide treating physicians with an overview of the rationale behind the emerging armamentarium against cGVHD.