Browsing by Subject "Cultured Endothelial Cells Endothelium"

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    Human umbilical cord blood-derived endothelial cells reendothelialize vein grafts and prevent thrombosis.
    (Arteriosclerosis, thrombosis, and vascular biology, 2010-11) Brown, MA; Zhang, L; Levering, VW; Wu, JH; Satterwhite, LL; Brian, L; Freedman, NJ; Truskey, GA
    OBJECTIVE: To accelerate vein graft reendothelialization and reduce vein graft thrombosis by infusing human umbilical cord blood-derived endothelial cells (hCB-ECs) because loss of endothelium contributes to vein graft thrombosis and neointimal hyperplasia. RESULTS: Under steady flow conditions in vitro, hCB-ECs adhered to smooth muscle cells 2.5 to 13 times more than ECs derived from peripheral blood or human aorta (P