Browsing by Subject "Fear"
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Item Open Access Anxiety as a determinant of differential responsivity to reward and punishment(1952) Barger, Benjamin, 1920-Reward and punishment have been studied in the laboratory for their relative effects on learning processes and on perceptual processes they have been studied in the classroom for their relative effects on learning and on modification of performance of various motor and mental tasks; they have been studied in relation to intellectual, age and sex factors, and temperamental or personality factors; and they have recently been studied in a clinical setting in connection with problems of psychopathology, The studies concerned with personality variables reflect a broadening concern with personality dynamics that has accompanied the recent rapid expansion of interest in the clinical area of psychology. They strongly suggest that there are differences related to personality factors in the effects and perhaps the effectiveness of rewarding and punishing incentive conditions. It was to explore some of the implications of these studies and to extend the empirical data in this area that the present research was designed. It was to explore some of the implications of these studies and to extend the empirical data in this area that the present research was designed. To provide a framework for the discussion which follows the major aspects of two studies will be outlined.Item Open Access Binding the Strong Man and the Outpost of Grace: A theological investigation of fear in young adults(2021) Davis, Preston AndrewsThis work unfolds in three moves to explore the rise in fear and anxiety in young adults and to provide a theological response from a chapel office on a college campus. The first move involves an exegetical reading of the Markan parable (adapted in Matthew) of “Binding the Strong Man”. This parable serves as an overarching metaphor for the nature of both the fearful realities many young adults find themselves in and the nature of the God who seeks to break into that reality and remind us of our innate value and worth in God. The parable asks us to think about whom we follow and call our leader, for whom we follow will form us at the deepest levels individually and collectively.
The second move of this thesis examines frameworks for understanding the anxious lives of young adults today: neurological, psychological, philosophical, and finally theological through an Augustinian lens. Through these frameworks we learn we need a renewed appreciation for the emotional life as the primary place of meaning making. Emotions are intelligent, that is, they have something to tell us about our deepest loves and desires. In particular, it investigates Augustine’s exploration of sophistry and philosophy as guides for constraining fear. Ironically, the deeper he found himself in those fields and frameworks the more disordered his inner life became. His personal experience and the values of ancient Rome serve as a warning for what happens when fear is allowed to run the lives of the ambitious individually and collectively.
The final move of the thesis is to take us into the outpost of grace, a location and people retraining their desires in the direction of Christ. This section highlights one prescriptive piece–that of retraining in belonging—to address the rise of loneliness and its interrelationship with anxiety. The outpost of grace provides new liturgies and habits to replace the cultural norms that disorder our inner lives.
Item Open Access Binding the Strong Man and the Outpost of Grace: A theological investigation of fear in young adults(2021) Davis, Preston AndrewsThis work unfolds in three moves to explore the rise in fear and anxiety in young adults and to provide a theological response from a chapel office on a college campus. The first move involves an exegetical reading of the Markan parable (adapted in Matthew) of “Binding the Strong Man”. This parable serves as an overarching metaphor for the nature of both the fearful realities many young adults find themselves in and the nature of the God who seeks to break into that reality and remind us of our innate value and worth in God. The parable asks us to think about whom we follow and call our leader, for whom we follow will form us at the deepest levels individually and collectively.
The second move of this thesis examines frameworks for understanding the anxious lives of young adults today: neurological, psychological, philosophical, and finally theological through an Augustinian lens. Through these frameworks we learn we need a renewed appreciation for the emotional life as the primary place of meaning making. Emotions are intelligent, that is, they have something to tell us about our deepest loves and desires. In particular, it investigates Augustine’s exploration of sophistry and philosophy as guides for constraining fear. Ironically, the deeper he found himself in those fields and frameworks the more disordered his inner life became. His personal experience and the values of ancient Rome serve as a warning for what happens when fear is allowed to run the lives of the ambitious individually and collectively.
The final move of the thesis is to take us into the outpost of grace, a location and people retraining their desires in the direction of Christ. This section highlights one prescriptive piece–that of retraining in belonging—to address the rise of loneliness and its interrelationship with anxiety. The outpost of grace provides new liturgies and habits to replace the cultural norms that disorder our inner lives.
Item Open Access Effective health communication - a key factor in fighting the COVID-19 pandemic.(Patient education and counseling, 2020-05) Finset, Arnstein; Bosworth, Hayden; Butow, Phyllis; Gulbrandsen, Pål; Hulsman, Robert L; Pieterse, Arwen H; Street, Richard; Tschoetschel, Robin; van Weert, JuliaItem Open Access Exercise-induced pain intensity predicted by pre-exercise fear of pain and pain sensitivity.(Clin J Pain, 2011-06) Bishop, Mark D; Horn, Maggie E; George, Steven ZOBJECTIVES: Our primary goals were to determine whether preexisting fear of pain and pain sensitivity contributed to post-exercise pain intensity. METHODS: Delayed-onset muscle pain was induced in the trunk extensors of 60 healthy volunteers using an exercise paradigm. Levels of fear of pain and experimental pain sensitivity were measured before exercise. Pain intensity in the low back was collected at 24 and 48 hours post-exercise. Participants were grouped based on pain intensity. Group membership was used as the dependent variable in separate regression models for 24 and 48 hours. Predictor variables included fear, pain sensitivity, torque lost during the exercise protocol, and demographic variables. RESULTS: The final models predicting whether a participant reported clinically meaningful pain intensity at 24 hours only included baseline fear of pain at each level of pain intensity tested. The final model at 48 hours included average baseline pain sensitivity and the loss of muscle performance during the exercise protocol for 1 level of pain intensity tested (greater than 35 mm of 100 mm). DISCUSSION: Combined, these findings suggest that the initial reports of pain after injury may be more strongly influenced by fear whereas the inflammatory process and pain sensitivity may play a larger role for later pain intensity reports.Item Open Access Fear learning circuitry is biased toward generalization of fear associations in posttraumatic stress disorder.(Transl Psychiatry, 2015-12-15) Morey, RA; Dunsmoor, JE; Haswell, CC; Brown, VM; Vora, A; Weiner, J; Stjepanovic, D; Wagner, HR; VA Mid-Atlantic MIRECC Workgroup; LaBar, KSFear conditioning is an established model for investigating posttraumatic stress disorder (PTSD). However, symptom triggers may vaguely resemble the initial traumatic event, differing on a variety of sensory and affective dimensions. We extended the fear-conditioning model to assess generalization of conditioned fear on fear processing neurocircuitry in PTSD. Military veterans (n=67) consisting of PTSD (n=32) and trauma-exposed comparison (n=35) groups underwent functional magnetic resonance imaging during fear conditioning to a low fear-expressing face while a neutral face was explicitly unreinforced. Stimuli that varied along a neutral-to-fearful continuum were presented before conditioning to assess baseline responses, and after conditioning to assess experience-dependent changes in neural activity. Compared with trauma-exposed controls, PTSD patients exhibited greater post-study memory distortion of the fear-conditioned stimulus toward the stimulus expressing the highest fear intensity. PTSD patients exhibited biased neural activation toward high-intensity stimuli in fusiform gyrus (P<0.02), insula (P<0.001), primary visual cortex (P<0.05), locus coeruleus (P<0.04), thalamus (P<0.01), and at the trend level in inferior frontal gyrus (P=0.07). All regions except fusiform were moderated by childhood trauma. Amygdala-calcarine (P=0.01) and amygdala-thalamus (P=0.06) functional connectivity selectively increased in PTSD patients for high-intensity stimuli after conditioning. In contrast, amygdala-ventromedial prefrontal cortex (P=0.04) connectivity selectively increased in trauma-exposed controls compared with PTSD patients for low-intensity stimuli after conditioning, representing safety learning. In summary, fear generalization in PTSD is biased toward stimuli with higher emotional intensity than the original conditioned-fear stimulus. Functional brain differences provide a putative neurobiological model for fear generalization whereby PTSD symptoms are triggered by threat cues that merely resemble the index trauma.Item Open Access Fear, avoidance and physiological symptoms during cognitive-behavioral therapy for social anxiety disorder.(Behav Res Ther, 2013-07) Aderka, Idan M; McLean, Carmen P; Huppert, Jonathan D; Davidson, Jonathan RT; Foa, Edna BWe examined fear, avoidance and physiological symptoms during cognitive-behavioral therapy (CBT) for social anxiety disorder (SAD). Participants were 177 individuals with generalized SAD who underwent a 14-week group CBT as part of a randomized controlled treatment trial. Participants filled out self-report measures of SAD symptoms at pre-treatment, week 4 of treatment, week 8 of treatment, and week 14 of treatment (post-treatment). Cross-lagged Structural Equation Modeling indicated that during the first 8 weeks of treatment avoidance predicted subsequent fear above and beyond previous fear, but fear did not predict subsequent avoidance beyond previous avoidance. However, during the last 6 weeks of treatment both fear and avoidance predicted changes in each other. In addition, changes in physiological symptoms occurred independently of changes in fear and avoidance. Our findings suggest that changes in avoidance spark the cycle of change in treatment of SAD, but the cycle may continue to maintain itself through reciprocal relationships between avoidance and fear. In addition, physiological symptoms may change through distinct processes that are independent from those involved in changes of fear and avoidance.Item Open Access Group Model Building on causes and interventions for falls in Singapore: insights from a systems thinking approach.(BMC geriatrics, 2023-09) Lai, Wei Xuan; Chan, Angelique Wei-Ming; Matchar, David Bruce; Ansah, John Pastor; Lien, Christopher Tsung Chien; Ismail, Noor Hafizah; Wong, Chek Hooi; Xu, Tianma; Ho, Vanda Wen Teng; Tan, Pey June; Lee, June May Ling; Sim, Rita Siew Choo; Manap, NormalaBackground
Falls in older adults are the result of a complex web of interacting causes, that further results in other physical, emotional, and psychological sequelae. A conceptual framework that represents the reciprocal dynamics of these causal factors can enable clinicians, researchers, and policymakers to clarify goals in falls intervention in older adults.Methods
A Group Model Building (GMB) exercise was conducted with researchers and clinicians from academic units and public healthcare institutes in Singapore. The aim of the exercise was to produce a shared visual representation of the causal structure for falls and engage in discussions on how current and future falls intervention programmes can address falls in the older adults, especially in the Asian context. It was conducted in four steps: 1) Outlining and prioritising desirable patient outcomes, 2) Conceptual model building, 3) Identifying key intervention elements of effective falls intervention programmes, 4) Mapping of interventions to outcomes. This causal loop diagram (CLD) was then used to generate insights into the current understanding of falls causal relationships, current efforts in falls intervention in Singapore, and used to identify gaps in falls research that could be further advanced in future intervention studies.Results
Four patient outcomes were identified by the group as key in falls intervention: 1) Falls, 2) Injurious falls, 3) Fear of falling, and 4) Restricted mobility and life space. A CLD of the reciprocal relationships between risk factors and these outcomes are represented in four sub-models: 1) Fear of falling, 2) Injuries associated with falls, 3) Caregiver overprotectiveness, 4) Post-traumatic stress disorder and psychological resilience. Through this GMB exercise, the group gained the following insights: (1) Psychological sequelae of falls is an important falls intervention outcome. (2) The effects of family overprotectiveness, psychological resilience, and PTSD in exacerbating the consequences of falls are not well understood. (3) There is a need to develop multi-component falls interventions to address the multitude of falls and falls related sequelae.Conclusion
This work illustrates the potential of GMB to promote shared understanding of complex healthcare problems and to provide a roadmap for the development of more effective preventive actions.Item Open Access Investigating dynamic pain sensitivity in the context of the fear-avoidance model.(Eur J Pain, 2015-01) Gay, CW; Horn, ME; Bishop, MD; Robinson, ME; Bialosky, JEBACKGROUND: Although nearly everyone at some point in their lives experiences back pain; the amount of interference with routine activity varies significantly. The fear-avoidance (FA) model of chronic pain explains how psychological variables, such as fear, act as mediating factors influencing the relationship between clinical pain intensity and the amount of interference with daily activities. What remains less clear is how other mediating factors fit within this model. The primary objective of this report was to examine the extent to which a dynamic measure of pain sensitivity provides additional information within the context of the FA model. METHOD: To address our primary objective, classic mediation and moderated mediation analyses were conducted on baseline clinical, psychological and quantitative sensory measures obtained on 67 subjects with back pain (mean age, 31.4 ± 12.1 years; 70% female). RESULTS: There was a moderately strong relationship (r = 0.52; p < 0.01) between clinical pain intensity and interference, explaining about 27% of the variance in the outcome. Mediation analyses confirmed fear partially mediated the total effect of clinical pain intensity on interference (Δβ = 0.27; p < 0.01), and accounted for an additional 16% of the variance. In our FA model, pain sensitivity did not demonstrate additional indirect effects; however, it did moderate the strength of indirect effects of fear. CONCLUSION: This preliminary modelling suggests complex interactions exist between pain-related fear and pain sensitivity measures that further explain individual differences in behaviour.Item Open Access Neuron-specific Sumo1-3 knockdown in mice impairs episodic and fear memories.(Journal of psychiatry & neuroscience : JPN, 2014-07) Wang, Liangli; Rodriguiz, Ramona M; Wetsel, William C; Sheng, Huaxin; Zhao, Shengli; Liu, Xiaozhi; Paschen, Wulf; Yang, WeiBACKGROUND:Growing evidence suggests that small ubiquitin-like modifier (SUMO) conjugation plays a key role in brain plasticity by modulating activity-dependent synaptic transmission. However, these observations are based largely on cell culture experiments. We hypothesized that episodic and fear memories would be affected by silencing SUMO1-3 expression. METHODS:To investigate the role of SUMO conjugation in neuronal functioning in vivo, we generated a novel Sumo transgenic mouse model in which a Thy1 promoter drives expression of 3 distinct microRNAs to silence Sumo1-3 expression, specifically in neurons. Wild-type and Sumo1-3 knockdown mice were subjected to a battery of behavioural tests to elucidate whether Sumoylation is involved in episodic and emotional memory. RESULTS:Expression of Sumo1-3 microRNAs and the corresponding silencing of Sumo expression were particularly pronounced in hippocampal, amygdala and layer V cerebral cortex neurons. The Sumo knockdown mice displayed anxiety-like responses and were impaired in episodic memory processes, contextual and cued fear conditioning and fear-potentiated startle. LIMITATIONS:Since expression of Sumo1-3 was silenced in this mouse model, we need to verify in future studies which of the SUMO paralogues play the pivotal role in episodic and emotional memory. CONCLUSION:Our results indicate that a functional SUMO conjugation pathway is essential for emotionality and cognition. This novel Sumo knockdown mouse model and the technology used in generating this mutant may help to reveal novel mechanisms that underlie a variety of neuropsychiatric conditions associated with anxiety and impairment of episodic and emotional memory.Item Open Access Sexual victimization, fear of sexual powerlessness, and cognitive emotion dysregulation as barriers to sexual assertiveness in college women.(Violence Against Women, 2013-12) Zerubavel, Noga; Messman-Moore, Terri LThe current study examined sexual victimization and two barriers to young women's sexual assertiveness: fear of sexual powerlessness and cognitive emotion dysregulation. College women (N = 499) responded to surveys and indicated that fear of sexual powerlessness and, to a lesser extent, cognitive emotion dysregulation were barriers to sexual assertiveness. Compared with nonvictims, sexually victimized women had greater problems with sexual assertiveness, fear of sexual powerlessness, and cognitive emotion dysregulation. Among victims, fear of sexual powerlessness and emotion dysregulation interacted to impede sexual assertiveness. Findings support targeting identified barriers in interventions to improve sexual assertiveness and reduce risk for unwanted sexual experiences and sexual victimization.