Browsing by Subject "Head"
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Item Open Access Pediatric Head and Neck Dynamic Response: A Computational Study(2011) Dibb, Alan ThomasTraumatic injuries are the leading cause of death to children between the ages of one to nineteen years in the United States. The primary source of these traumatic injuries is motor vehicle traffic, with the head being the primary region of the body to suffer injury. While the pediatric neck is also prone to injury, it is particularly notable since it governs head excursion and acceleration, thus influencing head impacts and injuries. Pediatric fatalities can be prevented through safety improvements to vehicle compartments and child restraints by way of advanced biofidelic pediatric anthropomorphic testing devices (ATDs) and a more complete understanding of pediatric biomechanics. Computer models of the pediatric head and neck provide a valuable tool to combine results from pediatric postmortem human specimen (PMHS), radiological, and human volunteer studies to investigate the dynamics of the pediatric head and neck. The current study produced the first validated computer model of the pediatric head and neck which were created using the framework of a validated adult model. Radiology studies were conducted to determine pediatric cervical muscle cross sectional areas, vertebral anthropometry, and vertebral inertial properties. The results of these studies were combined with available pediatric PMHS properties to create the six and ten year old models. The models were validated against pediatric volunteer low speed frontal impacts and were then used to simulate higher rate and injurious inducing loading scenarios. The six and ten year old flexion bending stiffnesses were found to be 36% and 45% of the adult bending stiffness, respectively. The pediatric tensile stiffnesses were found to be 67% and 76% of the adult tensile stiffness. The tensile failure tolerance of the six year old was between 1490 and 2300 N and of the ten year old between 2040 and 3170 N. The adult and pediatric Hybrid III ATDs were found to be on average 2.5 times stiffer in flexion bending than the computer models. Biofidelity corridors were created with the models to be used to guide future ATD designs. Overall, the pediatric models provide a general tool that can be used to assess the safety of children during motor vehicle crashes.
Item Open Access Piecewise Multivariate Linearity Between Kinematic Features and Cumulative Strain Damage Measure (CSDM) Across Different Types of Head Impacts.(Annals of biomedical engineering, 2022-11) Zhan, Xianghao; Li, Yiheng; Liu, Yuzhe; Cecchi, Nicholas J; Gevaert, Olivier; Zeineh, Michael M; Grant, Gerald A; Camarillo, David BIn a previous study, we found that the relationship between brain strain and kinematic features cannot be described by a generalized linear model across different types of head impacts. In this study, we investigate if such a linear relationship exists when partitioning head impacts using a data-driven approach. We applied the K-means clustering method to partition 3161 impacts from various sources including simulation, college football, mixed martial arts, and car crashes. We found piecewise multivariate linearity between the cumulative strain damage (CSDM; assessed at the threshold of 0.15) and head kinematic features. Compared with the linear regression models without partition and the partition according to the types of head impacts, K-means-based data-driven partition showed significantly higher CSDM regression accuracy, which suggested the presence of piecewise multivariate linearity across types of head impacts. Additionally, we compared the piecewise linearity with the partitions based on individual features used in clustering. We found that the partition with maximum angular acceleration magnitude at 4706 rad/s2 led to the highest piecewise linearity. This study may contribute to an improved method for the rapid prediction of CSDM in the future.Item Open Access Sexual selection and canine dimorphism in New World monkeys.(Am J Phys Anthropol, 1988-11) Kay, RF; Plavcan, JM; Glander, KE; Wright, PCSocial and ecological factors are important in shaping sexual dimorphism in Anthropoidea, but there is also a tendency for body-size dimorphism and canine dimorphism to increase with increased body size (Rensch's rule) (Rensch: Evolution Above the Species Level. London: Methuen, 1959.) Most ecologist interpret Rensch's rule to be a consequence of social and ecological selective factors that covary with body size, but recent claims have been advanced that dimorphism is principally a consequence of selection for increased body size alone. Here we assess the effects of body size, body-size dimorphism, and social structure on canine dimorphism among platyrrhine monkeys. Platyrrhine species examined are classified into four behavioral groups reflecting the intensity of intermale competition for access to females or to limiting resources. As canine dimorphism increases, so does the level of intermale competition. Those species with monogamous and polyandrous social structures have the lowest canine dimorphism, while those with dominance rank hierarchies of males have the most canine dimorphism. Species with fission-fusion social structures and transitory intermale breeding-season competition fall between these extremes. Among platyrrhines there is a significant positive correlation between body size and canine dimorphism However, within levels of competition, no significant correlation was found between the two. Also, with increased body size, body-size dimorphism tends to increase, and this correlation holds in some cases within competition levels. In an analysis of covariance, once the level of intermale competition is controlled for, neither molar size nor molar-size dimorphism accounts for a significant part of the variance in canine dimorphism. A similar analysis using body weight as a measure of size and dimorphism yields a less clear-cut picture: body weight contributes significantly to the model when the effects of the other factors are controlled. Finally, in a model using head and body length as a measure of size and dimorphism, all factors and the interactions between them are significant. We conclude that intermale competition among platyrrhine species is the most important factor explaining variations in canine dimorphism. The significant effects of size and size dimorphism in some models may be evidence that natural (as opposed to sexual) selection also plays a role in the evolution of increased canine dimorphism.Item Open Access Stimulation Efficiency With Decaying Exponential Waveforms in a Wirelessly Powered Switched-Capacitor Discharge Stimulation System.(IEEE transactions on bio-medical engineering, 2018-05) Lee, Hyung-Min; Howell, Bryan; Grill, Warren M; Ghovanloo, MaysamThe purpose of this study was to test the feasibility of using a switched-capacitor discharge stimulation (SCDS) system for electrical stimulation, and, subsequently, determine the overall energy saved compared to a conventional stimulator. We have constructed a computational model by pairing an image-based volume conductor model of the cat head with cable models of corticospinal tract (CST) axons and quantified the theoretical stimulation efficiency of rectangular and decaying exponential waveforms, produced by conventional and SCDS systems, respectively. Subsequently, the model predictions were tested in vivo by activating axons in the posterior internal capsule and recording evoked electromyography (EMG) in the contralateral upper arm muscles. Compared to rectangular waveforms, decaying exponential waveforms with time constants >500 μs were predicted to require 2%-4% less stimulus energy to activate directly models of CST axons and 0.4%-2% less stimulus energy to evoke EMG activity in vivo. Using the calculated wireless input energy of the stimulation system and the measured stimulus energies required to evoke EMG activity, we predict that an SCDS implantable pulse generator (IPG) will require 40% less input energy than a conventional IPG to activate target neural elements. A wireless SCDS IPG that is more energy efficient than a conventional IPG will reduce the size of an implant, require that less wireless energy be transmitted through the skin, and extend the lifetime of the battery in the external power transmitter.Item Open Access Studies of the Human Head from Neonate to Adult: An Inertial, Geometrical and Structural Analysis with Comparisons to the ATD Head(2011) Loyd, Andre MatthewChild head injury is a very costly problem, both in terms of morbidity/mortality and direct medical costs. In fact, it is the leading cause of death and disability for those in the United States under age 18-years-old. Currently, head injury in children ages newborn to 19-years-old is responsible for 7500 deaths per year--30% of all childhood deaths in the United States. Given its importance and effect on the population, the study of pediatric head injury is greatly hindered by the lack of available pediatric post mortem human specimen (PMHS) data. As a substitute for PMHS testing, anthropometric test devices (ATDs) and finite element models (FEMs) have been developed to model the head. However, there is a dearth of data for the design and validation of these models.
The goal of this study was to use pediatric PMHSs to both advance the study of pediatric head injury and to provide validation data for ATD and finite element head models. 14 pediatric heads, 8 adult heads, and 6 ATD heads were studied to obtain geometrical, inertial, structural stiffness, and impact properties. The computational tomography (CT) method was used on pediatric heads to get inertial properties, and clinical CT scans were used to develop average head and skull contours for 12 different age groups. To obtain impact properties, the heads were dropped onto a rigid plate from 15cm and 30cm, and the acceleration-time pulses were analyzed to obtain acceleration HIC and other impact properties. The heads were then placed between two aluminum plates and compressed at four different rates to obtain structural stiffness values. Using the PMHS results, the ATD heads were compared against age-matched human heads, and the scaling rules used for ATD production were tested for accuracy.
The study found that between the ages of 5-months-old and 22-months-old, the human head was susceptible to fracture from drops as low as 15cm. The structural stiffness of the human head was shown to increase by three orders of magnitude from neonate to adult. For the impact properties, the human head's peak acceleration and head injury criteria increased with age, while the human head's pulse duration and coefficient of restitution decreased with age. The 50th percentile Hybrid III head was found to adequately model the response of the adult head for multiple head impact locations, while the 3-year-old Q3 child ATD was found to be too stiff during impact. Overall, this study provides novel data that can be directly applied to pediatric head injury curves, and pediatric ATD and finite element head models.