Browsing by Subject "Mediation"
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Item Embargo Exploring the Mediating Effects of Depression on the Effectiveness of a Brief Negotiational Intervention in Reducing Harmful Alcohol Use in Moshi, Tanzania: A Mixed Method Study(2024) Buono , Mia KaitlinAlcohol Use Disorder (AUD) and Major Depressive Disorder (MDD) account for millions of deaths and disabilities each year with many theories on the interaction between the two disorders. Tanzania has a high rate of harmful alcohol use, depression, and alcohol-related injuries. To address the growing burden, a nurse-led Brief Negotiational Intervention (BNI) was implemented in the Kilimanjaro Christian Medical Centre Emergency Department in 2020. Three-month outcomes from this study have shown that AUDIT scores are not significantly reduced by the intervention. Thus, this study aims to explore the relationship and potential mediating effects of depression within the context of the BNI at KCMC ED. For quantitative aims, we used secondary data from the PRACT 6-month outcomes. We compared demographic characteristics between AUDIT/PHQ-9 categories using median, IQR, Kruskal-Wallis, and Fisher’s Exact Test. We then specified two cross-sectional structural equation models at 3 and 6 months to explore depression as a mediator between BNI and AUDIT scores. For our qualitative aim, we conducted 15 semi-structured interviews and analyzed data using a thematic coding approach. Out of our 282 participants, demographic characteristics differed between AUDIT/PHQ-9 groups on gender and education. Additionally, depression does not mediate the relationship between BNI and AUDIT scores at 3 or 6 months. However, BNI is reducing AUDIT and PHQ-9 scores at 6 months. Our qualitative data highlights the association between AUD and MDD and explores the importance of social communities for both disorders. More research is needed to determine the temporality between AUD and MDD in this context. Yet, this study has provided evidence that an alcohol-based BNI has provided benefits for AUD and MDD. Thus, it’s imperative to capitalize on this unintended intervention effect and modify the intervention to include a mental health component.
Item Open Access Mande Music in the Black Atlantic: Migration and the Affordances of World Music Record Production(2021) Henderson, Jonathan J.This multi-sited (or “patchwork”) ethnography (A.L. Tsing 2011, xi; Günel, Varma, and Watanabe 2020; Marcus 1995; A.L. Tsing 2015) examines how Mande music is remade in its circulation through world music industry networks of the Black Atlantic. I study how world music record producers work to reconcile ethical, aesthetic, and financial motivations in sound. Turning to Toumani Diabaté’s Kaira (1988), an influential world music album produced by ethnomusicologist Lucy Durán, I argue that this recording has been uniquely consequential in defining the sound of Mande music for Global North publics, and then I treat it as a case study to consider the ethics of cross-cultural record production. I show how Durán engages with a politics of invisibility to prioritize the careers of her collaborators, to cultivate ethnographic authority in her recording practice, and to create avenues for broad public appreciation of Mande music traditions, even as she effects alterations on the musical practices she proposes to reflect. Next, I illustrate how one Mande musician’s expressive practice is transformed by his migration to the Southern United States and by his interactions with the music industry in that context. Finally, I present a sonic exposition of twenty-six Mande music recordings that I myself produced as yet another frame in which to consider how Mande music is remade in circulation.
Item Open Access Sources of disconnection in neurocognitive aging: cerebral white-matter integrity, resting-state functional connectivity, and white-matter hyperintensity volume.(Neurobiol Aging, 2017-06) Madden, David J; Parks, Emily L; Tallman, Catherine W; Boylan, Maria A; Hoagey, David A; Cocjin, Sally B; Packard, Lauren E; Johnson, Micah A; Chou, Ying-Hui; Potter, Guy G; Chen, Nan-Kuei; Siciliano, Rachel E; Monge, Zachary A; Honig, Jesse A; Diaz, Michele TAge-related decline in fluid cognition can be characterized as a disconnection among specific brain structures, leading to a decline in functional efficiency. The potential sources of disconnection, however, are unclear. We investigated imaging measures of cerebral white-matter integrity, resting-state functional connectivity, and white-matter hyperintensity volume as mediators of the relation between age and fluid cognition, in 145 healthy, community-dwelling adults 19-79 years of age. At a general level of analysis, with a single composite measure of fluid cognition and single measures of each of the 3 imaging modalities, age exhibited an independent influence on the cognitive and imaging measures, and the imaging variables did not mediate the age-cognition relation. At a more specific level of analysis, resting-state functional connectivity of sensorimotor networks was a significant mediator of the age-related decline in executive function. These findings suggest that different levels of analysis lead to different models of neurocognitive disconnection, and that resting-state functional connectivity, in particular, may contribute to age-related decline in executive function.Item Open Access The Role of Self-Control, Social Support, and Reliance on Others in the Religiosity-Health Link(2015) Hopkin, CameronReligious observance has been reliably shown to improve a wide variety of health outcomes across the lifespan. Significant work has already been done to find mediating processes that explain this relationship, but as yet no studies have been published that attempt to integrate these mediators into a single model to see if they all work together. The current study presents three possible mediators of the religiosity-health link: social support, self-control, and reliance on others. Participants were recruited from Amazon.com’s Mechanical Turk worker system (N = 112) for a 14-day diary study in which all relevant constructs were measured on a daily basis, with daily health behaviors being the outcome. Social support, self-control, and reliance on others were all found to be simultaneous partial mediators of the religiosity-health link, though some questions remain as to the causal flow between religiosity and each of these mediators. It is concluded that each of these mechanisms is related to religiosity and in turn aid in the pursuit of superior health.