Browsing by Subject "Thailand"
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Item Open Access Knowledge, Cultural, and Structural Barriers to Thalassemia Screening in Migrant Populations in Thailand(2018) Xu, Julia ZheBackground: Thalassemia is a devastating inherited hematological disorder, and as a result of population migration, has become a global public health problem. Thailand has one of the highest burdens of thalassemia in the world and has developed a successful prevention and control program, but nearly 4 million migrants living in Thailand are excluded. Strategies for thalassemia screening in migrants are needed. This study aims to characterize migrants' awareness and knowledge of and attitudes toward thalassemia screening. Methods: 300 adult Myanmar or Cambodian migrant workers and 200 adult Thai citizens residing in the industrial province of Chonburi, Thailand were enrolled and given a demographic and KAP (Knowledge, Attitudes, and Practices) survey on thalassemia. Descriptive statistics, tabulations, Wilcoxon Rank Sum Tests, Kruskal-Wallis Test, and Chi-Square analysis were used to compare socio-demographic variables and levels of thalassemia awareness between migrant and Thai subjects. Results: Myanmar and Cambodian subjects had very low awareness of thalassemia, in contrast with Thai subjects (4.1% vs 79.6%, respectively). Migrants also had lower knowledge of thalassemia, but showed strong interest in thalassemia screening. Gender and education level predicted thalassemia awareness in Thai subjects, but length of residence in Thailand was the only demographic variable associated with awareness in migrants. Conclusions: This study revealed a tremendous awareness gap between Thai and migrant populations surrounding thalassemia, suggesting that public education is a crucial starting point for a thalassemia prevention and control program in migrants. A number of structural and cultural barriers identified in this study will also need to be addressed.
Item Open Access Lopinavir/ritonavir monotherapy after virologic failure of first-line antiretroviral therapy in resource-limited settings.(AIDS, 2012-07-17) Bartlett, John A; Ribaudo, Heather J; Wallis, Carole L; Aga, Evgenia; Katzenstein, David A; Stevens, Wendy S; Norton, Michael R; Klingman, Karin L; Hosseinipour, Mina C; Crump, John A; Supparatpinyo, Khuanchai; Badal-Faesen, Sharlaa; Kallungal, Beatrice A; Kumarasamy, NagalingeswaranOBJECTIVE: To evaluate virologic response rates of lopinavir/ritonavir (LPV/r) monotherapy as second-line antiretroviral treatment (ART) among adults in resource-limited settings (RLSs). DESIGN: An open-label pilot study of LPV/r monotherapy in participants on first-line nonnucleoside reverse transcriptase inhibitor three-drug combination ART with plasma HIV-1 RNA 1000-200 000 copies/ml. METHODS: Participants were recruited from five sites in Africa and Asia within the AIDS Clinical Trials Group (ACTG) network. All participants received LPV/r 400/100 mg twice daily. The primary endpoint was remaining on LPV/r monotherapy without virologic failure at week 24. Participants with virologic failure were offered addition of emtricitabine and tenofovir (FTC/TDF) to LPV/r. RESULTS: Mutations associated with drug resistance were encountered in nearly all individuals screened for the study. One hundred and twenty-three participants were enrolled, and 122 completed 24 weeks on study. A high proportion remained on LPV/r monotherapy without virologic failure at 24 weeks (87%). Archived samples with HIV-1 RNA levels less than 400 copies/ml at week 24 (n=102) underwent ultrasensitive assay. Of these individuals, 62 had levels less than 40 copies/ml and 30 had levels 40-200 copies/ml. Fifteen individuals experienced virologic failure, among whom 11 had resistance assessed and two had emergent protease inhibitor mutations. Thirteen individuals with virologic failure added FTC/TDF and one individual added FTC/TDF without virologic failure. At study week 48, 11 of 14 adding FTC/TDF had HIV-1 RNA levels less than 400 copies/ml. CONCLUSION: In this pilot study conducted in diverse RLS, LPV/r monotherapy as second-line ART demonstrated promising activity.Item Open Access The Demand for Businessperson Politicians: How Do Businesspeople Win Electoral Nominations and Votes?(2023) Nillasithanukroh, SongkhunBusinesspeople are a highly represented occupational group in the governments of many countries. What electoral strategies do these businessperson politicians employ that afford them high electoral success? In a context where non-programmatic electoral strategies are common and when faced with strong constraints on the utilization of personal, party, and public resources for distributive purposes, I argue that businessperson candidates' access to private sector resources provides them with an alternative set of distributive resources that can be used to pursue political support, thereby granting businessperson candidates with an electoral advantage over other occupational groups.
Businessperson candidates are able to distribute private sector jobs to build an army of political workers who can provide political services. To test my arguments, I conducted list experiments with 986 employees in firms of businessperson candidates in Thailand. I find that employees in firms of businessperson candidates provide political services such as voting for the businessperson candidate, attending rallies, persuading acquaintances to support the businessperson candidate, and distributing goods and services produced by the firm to voters. Businessperson candidates, however, face a risk of shirking by patronage employees once hired. To overcome the commitment problem, I find that businessperson candidates rely on monitoring and negative inducements, in the form of employment termination threats, to mobilize these patronage employees to provide political services.
Item Open Access The reappearance hypothesis revisited: recurrent involuntary memories after traumatic events and in everyday life.(Mem Cognit, 2008-03) Berntsen, Dorthe; Rubin, David CRecurrent involuntary memories are autobiographical memories that come to mind with no preceding retrieval attempt and that are subjectively experienced as being repetitive. Clinically, they are classified as a symptom of posttraumatic stress disorder. The present work is the first to systematically examine recurrent involuntary memories outside clinical settings. Study 1 examines recurrent involuntary memories among survivors of the tsunami catastrophe in Southeast Asia in 2004. Study 2 examines recurrent involuntary memories in a large general population. Study 3 examines whether the contents of recurrent involuntary memories recorded in a diary study are duplicates of, or differ from, one another. We show that recurrent involuntary memories are not limited to clinical populations or to emotionally negative experiences; that they typically do not come to mind in a fixed and unchangeable form; and that they show the same pattern regarding accessibility as do autobiographical memories in general. We argue that recurrent involuntary memories after traumas and in everyday life can be explained in terms of general and well-established mechanisms of autobiographical memory.