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Now showing items 3213-3232 of 20727
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C-C Motif Chemokine 5 Attenuates Angiotensin II-Dependent Kidney Injury by Limiting Renal Macrophage Infiltration.
(Am J Pathol, 2016-11)Inappropriate activation of the renin angiotensin system (RAS) is a key contributor to the pathogenesis of essential hypertension. During RAS activation, infiltration of immune cells into the kidney exacerbates hypertension ... -
c-Myc is required for maintenance of glioma cancer stem cells.
(PLoS One, 2008)BACKGROUND: Malignant gliomas rank among the most lethal cancers. Gliomas display a striking cellular heterogeneity with a hierarchy of differentiation states. Recent studies support the existence of cancer stem cells in ... -
C-reactive protein, fibrinogen, and cardiovascular disease prediction.
(The New England journal of medicine, 2012-10)There is debate about the value of assessing levels of C-reactive protein (CRP) and other biomarkers of inflammation for the prediction of first cardiovascular events.We analyzed data from 52 prospective studies that included ... -
C. elegans germline-deficient mutants respond to pathogen infection using shared and distinct mechanisms.
(PLoS One, 2010-07-26)Reproduction extracts a cost in resources that organisms are then unable to utilize to deal with a multitude of environmental stressors. In the nematode C. elegans, development of the germline shortens the lifespan of the ... -
C4 article: Implications of COVID-19 in transplantation.
(American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2020-10-11)A novel coronavirus has had global impact on individual health and health care delivery. In this C4 article, contributors discuss various aspects of transplantation including donor and recipient screening, management of ... -
Ca2+ channel nanodomains boost local Ca2+ amplitude.
(Proc Natl Acad Sci U S A, 2013-09-24)Local Ca(2+) signals through voltage-gated Ca(2+) channels (CaVs) drive synaptic transmission, neural plasticity, and cardiac contraction. Despite the importance of these events, the fundamental relationship between flux ... -
Ca2+-Mediated Thermal Sensing in Plants
(2017)Temperature is an omnipresent environmental factor that shapes the growth, development and survival of plants. However, global warming has been an inevitable process and caused unusual temperature patterns across the world. ... -
Cabaret Identity: How Best to Play a Jew or Pass as a Gentile in Wartime Poland
(Journal of Jewish Identities, 2014) -
"Cabaret Identity: How Best to Play a Jew or Pass as a Gentile in Wartime Poland"
(Journal of Jewish Identities, 2014-07) -
CABG or PCI for Diabetic Patients With Left Ventricular Dysfunction: Closing in on the Truth?
(Journal of the American College of Cardiology, 2018-02) -
Cable Driven Multi-Articulating Fingers, Providing Compliant Grasp For The Partial Hand Amputee.
(2008)This article will describe a new concept in fitting the partial hand amputee to offer them enhanced grasp and improve their overall functional ability with the prosthesis. The concept is to activate the mechanical fingers ... -
Cadherin-Mediated Cell-Cell Interactions Regulates Phenotype And Morphology of Nucleus Pulposus Cells Of The Intervertebral Disc
(2015)Juvenile nucleus pulposus (NP) cells of the intervertebral disc (IVD) are large, vacuolated cells that form cell clusters with numerous cell-cell interactions. With maturation and aging, NP cells lose their ability to form ... -
CAFOs as Hotspots: Effect on Ecosystem Services and Needed Change in Environmental Leadership
(2012-04-27)Many Americans are neither aware that 99 percent of their meat consumed in the United States is produced by large-scale factory farms; nor, are they aware of the deleterious effect these operations have on environmental ... -
Calabi–Yau Monopoles for the Stenzel Metric
(Communications in Mathematical Physics, 2016-01) -
Calcineurin activation causes retinal ganglion cell degeneration.
(Mol Vis, 2012)PURPOSE: We previously reported that calcineurin, a Ca(2+)/calmodulin-dependent serine/threonine phosphatase, is activated and proposed that it participates in retinal ganglion cell (RGC) apoptosis in two rodent ... -
Calcineurin Targets Involved in Stress Survival and Fungal Virulence.
(PLoS Pathog, 2016-09)Calcineurin governs stress survival, sexual differentiation, and virulence of the human fungal pathogen Cryptococcus neoformans. Calcineurin is activated by increased Ca2+ levels caused by stress, and transduces signals ... -
Calcium Dependence of Fibrin Nanomechanics: The gamma 1 Calcium Mediates the Unfolding of Fibrinogen Induced by Force Applied to the "A-a" Bond
(2010)The interactions between the constituent monomers of fibrin, the polymerized protein network that provides the structural stability of blood clots, ale frequently under stress because of the dynamic nature of blood flow ... -
Calcium dependent CAMTA1 in adult stem cell commitment to a myocardial lineage.
(PLoS One, 2012)The phenotype of somatic cells has recently been found to be reversible. Direct reprogramming of one cell type into another has been achieved with transduction and over expression of exogenous defined transcription factors ... -
Calcium Pyrophosphate And Monosodium Urate Activate The NLRP3 Inflammasome Within Bladder Urothelium Via Reactive Oxygen Species And TXNIP.
(Research and reports in urology, 2019-01)Objective:To investigate the in vitro activation of the NLRP3 inflammasome within bladder urothelium by stone-forming components. Further, to describe the contributions of reactive oxygen species (ROS) and thioredoxin-interacting ...
