Browsing by Author "0011931"
Now showing items 21-35 of 35
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REGULATION OF THALAMIC ACTIVITY FOR CONTROL OF AGGRESSION
(2019-01-31) -
Revisiting the monoamine hypothesis of depression: a new perspective.
(Perspect Medicin Chem, 2014)As the incidence of depression increases, depression continues to inflict additional suffering to individuals and societies and better therapies are needed. Based on magnetic resonance spectroscopy and laboratory findings, ... -
Selected Gamma Aminobutyric Acid (GABA) Esters may Provide Analgesia for Some Central Pain Conditions.
(Perspect Medicin Chem, 2010-08-03)Central pain is an enigmatic, intractable condition, related to destruction of thalamic areas, resulting in likely loss of inhibitory synaptic transmission mediated by GABA. It is proposed that treatment of central pain, ... -
Stereochemical basis for a unified structure activity theory of aromatic and heterocyclic rings in selected opioids and opioid peptides.
(Perspectives in medicinal chemistry, 2010-02-18)This paper presents a novel unified theory of the structure activity relationship of opioids and opioid peptides. It is hypothesized that a virtual or known heterocyclic ring exists in all opioids which have activity in ... -
Stereocomplexes Formed From Select Oligomers of Polymer d-lactic Acid (PDLA) and l-lactate May Inhibit Growth of Cancer Cells and Help Diagnose Aggressive Cancers-Applications of the Warburg Effect.
(Perspect Medicin Chem, 2011-02-15)It is proposed that select oligomers of polymer d-lactic acid (PDLA) will form a stereocomplex with l-lactate in vivo, producing lactate deficiency in tumor cells. Those cancer cells that utilize transport of lactate to ... -
SYNTHESIS AND IN VITRO ACTIVITY OF D-LACTIC ACID OLIGOMERS
(2018-09-27)This invention describes the synthesis and pharmacologic activity of n = 2 , n = 3 , n = 4 , n = 5 , and n = 6 D - lactic acid oligomers . D - lactic acid dimer has pharmacologic activity and sequesters L - lactate , and ... -
THERMODYNAMIC MODEL OF A NERVOUS SYSTEM
(2015-12-31) -
TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS WITH LACTATE
(2016-09-22) -
VITELLINE MEMBRANE AS A MODEL OF THE BLOOD BRAIN BARRIER
(2017-10-19)
