Browsing by Subject "Neurons"
Now showing items 21-40 of 105
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Coherence potentials: loss-less, all-or-none network events in the cortex.
(PLoS Biol, 2010-01-12)Transient associations among neurons are thought to underlie memory and behavior. However, little is known about how such associations occur or how they can be identified. Here we recorded ongoing local field potential (LFP) ... -
Convergent differential regulation of SLIT-ROBO axon guidance genes in the brains of vocal learners.
(J Comp Neurol, 2015-04-15)Only a few distantly related mammals and birds have the trait of complex vocal learning, which is the ability to imitate novel sounds. This ability is critical for speech acquisition and production in humans, and is attributed ... -
Coordinated multiplexing of information about separate objects in visual cortex.
(eLife, 2022-11)Sensory receptive fields are large enough that they can contain more than one perceptible stimulus. How, then, can the brain encode information about each of the stimuli that may be present at a given moment? We recently ... -
Cortical dynamics during naturalistic sensory stimulations: experiments and models.
(Journal of physiology, Paris, 2011-01)We report the results of our experimental and theoretical investigations of the neural response dynamics in primary visual cortex (V1) during naturalistic visual stimulation. We recorded Local Field Potentials (LFPs) and ... -
Delay activity of saccade-related neurons in the caudal dentate nucleus of the macaque cerebellum.
(J Neurophysiol, 2013-04)The caudal dentate nucleus (DN) in lateral cerebellum is connected with two visual/oculomotor areas of the cerebrum: the frontal eye field and lateral intraparietal cortex. Many neurons in frontal eye field and ... -
Development of a simplified spinal cord ischemia model in mice.
(Journal of neuroscience methods, 2010-06)Use of genetically manipulated mice facilitates understanding pathological mechanisms in many diseases and contributes to therapy development. However, there is no practical and clinically relevant mouse model available ... -
Differential Apaf-1 levels allow cytochrome c to induce apoptosis in brain tumors but not in normal neural tissues.
(Proc Natl Acad Sci U S A, 2007-12-26)Brain tumors are typically resistant to conventional chemotherapeutics, most of which initiate apoptosis upstream of mitochondrial cytochrome c release. In this study, we demonstrate that directly activating apoptosis downstream ... -
Differentiating sensitivity of post-stimulus undershoot under diffusion weighting: implication of vascular and neuronal hierarchy.
(PLoS One, 2008-08-13)The widely used blood oxygenation level dependent (BOLD) signal during brain activation, as measured in typical fMRI methods, is composed of several distinct phases, the last of which, and perhaps the least understood, is ... -
Division of labor in frontal eye field neurons during presaccadic remapping of visual receptive fields.
(J Neurophysiol, 2012-10)Our percept of visual stability across saccadic eye movements may be mediated by presaccadic remapping. Just before a saccade, neurons that remap become visually responsive at a future field (FF), which anticipates the saccade ... -
Dopamine receptors in a songbird brain.
(J Comp Neurol, 2010-03-15)Dopamine is a key neuromodulatory transmitter in the brain. It acts through dopamine receptors to affect changes in neural activity, gene expression, and behavior. In songbirds, dopamine is released into the striatal song ... -
Drivers from the deep: the contribution of collicular input to thalamocortical processing.
(Prog Brain Res, 2005)A traditional view of the thalamus is that it is a relay station which receives sensory input and conveys this information to cortex. This sensory input determines most of the properties of first order thalamic neurons, ... -
Effective spread and timecourse of neural inactivation caused by lidocaine injection in monkey cerebral cortex.
(J Neurosci Methods, 1997-06-06)We studied the effective spread of lidocaine to inactivate neural tissue in the frontal cortex of the rhesus monkey. Injections of 2% lidocaine at 4 microl/min were made while units were recorded 1 or 2 mm away. To inactivate ... -
Effects of frequency-dependent membrane capacitance on neural excitability.
(Journal of neural engineering, 2015-10)<h4>Objective</h4>Models of excitable cells consider the membrane specific capacitance as a ubiquitous and constant parameter. However, experimental measurements show that the membrane capacitance declines with increasing ... -
Electrically evoked saccades from the dorsomedial frontal cortex and frontal eye fields: a parametric evaluation reveals differences between areas.
(Exp Brain Res, 1997-12)Using electrical stimulation to evoke saccades from the dorsomedial frontal cortex (DMFC) and frontal eye fields (FEF) of rhesus monkeys, parametric tests were conducted to compare the excitability properties of these regions. ... -
Estimating network parameters from combined dynamics of firing rate and irregularity of single neurons.
(Journal of neurophysiology, 2011-01)High firing irregularity is a hallmark of cortical neurons in vivo, and modeling studies suggest a balance of excitation and inhibition is necessary to explain this high irregularity. Such a balance must be generated, at ... -
Evaluation and resolution of many challenges of neural spike sorting: a new sorter.
(Journal of neurophysiology, 2021-12)We evaluate existing spike sorters and present a new one that resolves many sorting challenges. The new sorter, called "full binary pursuit" or FBP, comprises multiple steps. First, it thresholds and clusters to identify ... -
Feasibility of Interferential and Pulsed Transcranial Electrical Stimulation for Neuromodulation at the Human Scale.
(Neuromodulation : journal of the International Neuromodulation Society, 2021-07)<h4>Objectives</h4>Transcranial electrical stimulation (tES) is a promising tool for modulating neural activity, but tES has poor penetrability and spatiotemporal resolution compared to invasive techniques like deep brain ... -
For whom the bird sings: context-dependent gene expression.
(Neuron, 1998-10)Male zebra finches display two song behaviors: directed and undirected singing. The two differ little in the vocalizations produced but greatly in how song is delivered. "Directed" song is usually accompanied by a courtship ... -
FoxP2 expression in avian vocal learners and non-learners.
(J Neurosci, 2004-03-31)Most vertebrates communicate acoustically, but few, among them humans, dolphins and whales, bats, and three orders of birds, learn this trait. FOXP2 is the first gene linked to human speech and has been the target of positive ...
