Browsing by Subject "Reproducibility of Results"
Now showing items 21-40 of 106
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Design and in vivo evaluation of more efficient and selective deep brain stimulation electrodes.
(Journal of neural engineering, 2015-08)<h4>Objective</h4>Deep brain stimulation (DBS) is an effective treatment for movement disorders and a promising therapy for treating epilepsy and psychiatric disorders. Despite its clinical success, the efficiency and selectivity ... -
Design of the NIDA clinical trials network validation study of tobacco, alcohol, prescription medications, and substance use/misuse (TAPS) tool.
(Contemporary clinical trials, 2016-09)Substance use and its associated use disorders are under-detected and under-treated in primary care. There is a need for a clinically useful brief screening and assessment instrument to identify primary care patients with ... -
Detection of depression in low resource settings: validation of the Patient Health Questionnaire (PHQ-9) and cultural concepts of distress in Nepal.
(BMC Psychiatry, 2016-03-08)BACKGROUND: Despite recognition of the burden of disease due to mood disorders in low- and middle-income countries, there is a lack of consensus on best practices for detecting depression. Self-report screening tools, such ... -
Development and implementation of a proficiency testing program for Luminex bead-based cytokine assays.
(Journal of Immunological Methods, 2014-07)Luminex bead array assays are widely used for rapid biomarker quantification due to the ability to measure up to 100 unique analytes in a single well of a 96-well plate. There has been, however, no comprehensive analysis ... -
Development of a contemporary globally diverse HIV viral panel by the EQAPOL program.
(J Immunol Methods, 2014-07)The significant diversity among HIV-1 variants poses serious challenges for vaccine development and for developing sensitive assays for screening, surveillance, diagnosis, and clinical management. Recognizing a need to develop ... -
Diagnostic performance of short portable mental status questionnaire for screening dementia among patients attending cognitive assessment clinics in Singapore.
(Annals of the Academy of Medicine, Singapore, 2013-07)<h4>Introduction</h4>The Short Portable Mental Status Questionnaire (SPMSQ) is a brief cognitive screening instrument, which is easy to use by a healthcare worker with little training. However, the validity of this instrument ... -
Dual-energy micro-CT functional imaging of primary lung cancer in mice using gold and iodine nanoparticle contrast agents: a validation study.
(PLoS One, 2014)PURPOSE: To provide additional functional information for tumor characterization, we investigated the use of dual-energy computed tomography for imaging murine lung tumors. Tumor blood volume and vascular permeability were ... -
Elevational ranges of birds on a tropical montane gradient lag behind warming temperatures.
(PloS one, 2011-01)<h4>Background</h4>Species may respond to a warming climate by moving to higher latitudes or elevations. Shifts in geographic ranges are common responses in temperate regions. For the tropics, latitudinal temperature gradients ... -
Elucidating the Molecular Composition of Cartilage by Proteomics.
(J Proteome Res, 2016-02-05)Articular cartilage consists of chondrocytes and two major components, a collagen-rich framework and highly abundant proteoglycans. Most prior studies defining the zonal distribution of cartilage have extracted proteins ... -
Emerging contaminant or an old toxin in disguise? Silver nanoparticle impacts on ecosystems.
(Environ Sci Technol, 2014-05-06)The use of antimicrobial silver nanoparticles (AgNPs) in consumer-products is rising. Much of these AgNPs are expected to enter the wastewater stream, with up to 10% of that eventually released as effluent into aquatic ecosystems ... -
Emotion and autobiographical memory: considerations from posttraumatic stress disorder.
(Phys Life Rev, 2010-03) -
Enhancing imaging systems using transformation optics.
(Opt Express, 2010-09-27)We apply the transformation optical technique to modify or improve conventional refractive and gradient index optical imaging devices. In particular, when it is known that a detector will terminate the paths of rays over ... -
Entorhinal cortex volume in older adults: reliability and validity considerations for three published measurement protocols.
(J Int Neuropsychol Soc, 2010-09)Measuring the entorhinal cortex (ERC) is challenging due to lateral border discrimination from the perirhinal cortex. From a sample of 39 nondemented older adults who completed volumetric image scans and verbal memory indices, ... -
Establishment and maintenance of a PBMC repository for functional cellular studies in support of clinical vaccine trials.
(J Immunol Methods, 2014-07)A large repository of cryopreserved peripheral blood mononuclear cells (PBMCs) samples was created to provide laboratories testing the specimens from human immunodeficiency virus-1 (HIV-1) vaccine clinical trials the material ... -
Evaluating marker-guided treatment selection strategies.
(Biometrics, 2014-09)A potential venue to improve healthcare efficiency is to effectively tailor individualized treatment strategies by incorporating patient level predictor information such as environmental exposure, biological, and genetic ... -
Evaluating renal lesions using deep-learning based extension of dual-energy FoV in dual-source CT-A retrospective pilot study.
(European journal of radiology, 2021-06)<h4>Purpose</h4>Dual-source (DS) CT, dual-energy (DE) field of view (FoV) is limited to the size of the smaller detector array. The purpose was to establish a deep learning-based approach to DE extrapolation by estimating ... -
Examining the factor structure of the Connor-Davidson Resilience Scale (CD-RISC) in a post-9/11 U.S. military veteran sample.
(Assessment, 2014-08)The present study examined the structural validity of the 25-item Connor-Davidson Resilience Scale (CD-RISC) in a large sample of U.S. veterans with military service since September 11, 2001. Participants (N = 1,981) completed ... -
Factors affecting pitch discrimination performance in a cohort of extensively phenotyped healthy volunteers.
(Scientific reports, 2017-11-28)Despite efforts to characterize the different aspects of musical abilities in humans, many elements of this complex area remain unknown. Musical abilities are known to be associated with factors like intelligence, training, ... -
Finding our way through phenotypes.
(PLoS Biol, 2015-01)Despite a large and multifaceted effort to understand the vast landscape of phenotypic data, their current form inhibits productive data analysis. The lack of a community-wide, consensus-based, human- and machine-interpretable ... -
Gastroesophageal reflux symptoms are not sufficient to guide esophageal function testing in lung transplant candidates.
(Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus, 2018-05)Gastroesophageal reflux disease and esophageal dysmotility are prevalent in patients with advanced lung disease and are associated with graft dysfunction following lung transplantation. As a result, many transplant centers ...
