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Now showing items 6889-6908 of 17366
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G protein beta gamma subunits stimulate phosphorylation of Shc adapter protein.
(Proc Natl Acad Sci U S A, 1995-09-26)The mechanism of mitogen-activated protein (MAP) kinase activation by pertussis toxin-sensitive Gi-coupled receptors is known to involve the beta gamma subunits of heterotrimeric G proteins (G beta gamma), p21ras activation, ... -
G protein signaling and vein graft intimal hyperplasia: reduction of intimal hyperplasia in vein grafts by a Gbetagamma inhibitor suggests a major role of G protein signaling in lesion development.
(Arterioscler Thromb Vasc Biol, 1998-08)Vein grafting results in the development of intimal hyperplasia with accompanying changes in guanine nucleotide-binding (G) protein expression and function. Several serum mitogens that act through G protein-coupled receptors, ... -
G Protein Signaling and Vein Graft Intimal Hyperplasia: Reduction of Intimal Hyperplasia in Vein Grafts by a Gbg Inhibitor
(1998-08)Abstract—Vein grafting results in the development of intimal hyperplasia with accompanying changes in guanine nucleotide–binding (G) protein expression and function. Several serum mitogens that act through G protein–coupled ... -
G proteins in medicine.
(N Engl J Med, 1995-01-19) -
G-protein-coupled receptor genes as protooncogenes: constitutively activating mutation of the alpha 1B-adrenergic receptor enhances mitogenesis and tumorigenicity.
(Proc Natl Acad Sci U S A, 1991-12-15)The alpha 1B-adrenergic receptor (alpha 1B-ADR) is a member of the G-protein-coupled family of transmembrane receptors. When transfected into Rat-1 and NIH 3T3 fibroblasts, this receptor induces focus formation ... -
G<inf>2</inf>-Monopoles with Singularities (Examples)
(Letters in Mathematical Physics, 2016-11-01)© 2016, Springer Science+Business Media Dordrecht.G2-Monopoles are solutions to gauge theoretical equations on G2-manifolds. If the G2-manifolds under consideration are compact, then any irreducible G2-monopole must have ... -
GaAsBi Synthesis: From Band Structure Modification to Nanostructure Formation
(2017)Research and development bismides have proven bismides to be a promising field for material science with important applications in optoelectronics. However, the development of a complete description of the electrical and ... -
Gabon’s Overlooked Carbon: A tropical forest study of coarse woody debris
(2013-04-26)Large dead trees and other large forest detritus (collectively known as coarse woody debris, or CWD) play an important role in the global carbon cycle. In tropical systems, CWD stocks (necromass) have been found to constitute ... -
Gaga, a new fern genus segregated from cheilanthes (pteridaceae)
(Systematic Botany, 2012-10-01)Ongoing molecular phylogenetic studies of cheilanthoid ferns confirm that the genus Cheilanthes (Pteridaceae) is polyphyletic. A monophyletic group of species within the hemionitid clade informally called the "C. marginata ... -
Gaining Competitive Advantage from Human Capital: Role of Markets and Firm Structure
(2015)This dissertation develops new theory and evidence to show that human-capital based competitive advantage of firms varies with external markets, firm structure, and firm openness to factor markets. The dissertation includes ... -
Gait and behavior in an IL1β-mediated model of rat knee arthritis and effects of an IL1 antagonist.
(J Orthop Res, 2011-05)Interleukin-1 beta (IL1β) is a proinflammatory cytokine that mediates arthritic pathologies. Our objectives were to evaluate pain and limb dysfunction resulting from IL1β over-expression in the rat knee and to investigate ... -
Galactokinase is a Novel Modifier of Calcineurin-Induced Cardiomyopathy in Drosophila
(2014)Calcineurin is both necessary and sufficient to induce cardiac hypertrophy, an independent risk factor for arrhythmia, dilated cardiomyopathy, heart failure, and sudden cardiac death. However, current knowledge of the downstream ... -
Gallium plasmonics: deep subwavelength spectroscopic imaging of single and interacting gallium nanoparticles.
(ACS Nano, 2015-02-24)Gallium has recently been demonstrated as a phase-change plasmonic material offering UV tunability, facile synthesis, and a remarkable stability due to its thin, self-terminating native oxide. However, the dense irregular ... -
Gallium-based Ultraviolet Nanoplasmonics
(2013)Nanometer-scale metallic structures have been widely and intensively studied over the last decade because of their remarkable plasmonic properties that can enhance local electromagnetic (EM) fields. However, most plasmonic ... -
Game Theory and Cold War Rationality: A Review Essay
(Economic Research Initiatives at Duke (ERID), 2016-02-23)This essay reviews new histories of the role of game theory and rational decision-making in shaping the social sciences, economics among them, in the post war period. The recent books "The World the Game Theorists Made" ... -
Game-Theoretic Question Selection for Tests
(JOURNAL OF ARTIFICIAL INTELLIGENCE RESEARCH, 2017) -
Game-Theoretically Allocating Resources to Catch Evaders and Payments to Stabilize Teams
(2016)Allocating resources optimally is a nontrivial task, especially when multipleself-interested agents with conflicting goals are involved. This dissertationuses techniques from game theory to study two classes of ... -
Gamification for Behavior Change of Occupants in Campus Buildings to Affect Improved Energy Efficiency
(2014-04-23)In 2012, 40% of total U.S. energy consumption was attributed to residential and commercial buildings. However, in order to improve building energy efficiency, most conservation measures adopted today are based on technologies ... -
Gap Analysis of Five Orders in Great Smoky Mountain National Park: A Quantification of Inventory Gaps
(2016-04-21)Global biodiversity is currently in a state of crisis with human alterations to the environment exacerbating extinctions so that extinction rates now exceed 1,000 times normal background rates (Lees & Pimm, 2015, Nicholas ... -
Gap Junctions Contribute to Differential Light Adaptation across Direction-Selective Retinal Ganglion Cells.
(Neuron, 2018-10)Direction-selective ganglion cells (DSGCs) deliver signals from the retina to multiple brain areas to indicate the presence and direction of motion. Delivering reliable signals in response to motion is critical across light ...
