Browsing by Affiliation of Duke Author(s) "Anesthesiology, Ambulatory"

Ambulatory continuous peripheral nerve blocks to treat postamputation phantom limb pain: a multicenter, randomized, quadruple-masked, placebo-controlled clinical trial.

Ilfeld, Brian M; Khatibi, Bahareh; Maheshwari, Kamal; Madison, Sarah J; Esa, Wael Ali Sakr; Mariano, Edward R; Kent, Michael L; ... (16 authors) (Pain, 2021-03)

Phantom limb pain is thought to be sustained by reentrant neural pathways, which provoke dysfunctional reorganization in the somatosensory cortex. We hypothesized that disrupting reentrant pathways with a 6-day-long continuous ...

Changes in Brain Resting-state Functional Connectivity Associated with Peripheral Nerve Block: A Pilot Study.

Melton, M Stephen; Browndyke, Jeffrey N; Harshbarger, Todd B; Madden, David J; Nielsen, Karen C; Klein, Stephen M (Anesthesiology, 2016-08)

BACKGROUND: Limited information exists on the effects of temporary functional deafferentation (TFD) on brain activity after peripheral nerve block (PNB) in healthy humans. Increasingly, resting-state functional connectivity ...

The Impact of Surgical Amputation and Valproic Acid on Pain and Functional Trajectory: Results from the Veterans Integrated Pain Evaluation Research (VIPER) Randomized, Double-Blinded Placebo-Controlled Trial.

Buchheit, Thomas; Hsia, Hung-Lun John; Cooter, Mary; Shortell, Cynthia; Kent, Michael; McDuffie, Mary; Shaw, Andrew; ... (9 authors) (Pain medicine (Malden, Mass.), 2019-05-02)

OBJECTIVE:To determine if the perioperative administration of valproic acid reduces the incidence of chronic pain three months after amputation or revision surgery. DESIGN:Multicenter, randomized, double-blind, placebo-controlled ...