Browsing by Affiliation of Duke Author(s) "Anesthesiology, Pain Management"

Genetic variant rs3750625 in the 3'UTR of ADRA2A affects stress-dependent acute pain severity after trauma and alters a microRNA-34a regulatory site.

Linnstaedt, Sarah D; Walker, Margaret G; Riker, Kyle D; Nyland, Jennifer E; Hu, JunMei; Rossi, Catherine; Swor, Robert A; ... (12 authors) (Pain, 2017-02)

α2A adrenergic receptor (α2A-AR) activation has been shown in animal models to play an important role in regulating the balance of acute pain inhibition vs facilitation after both physical and psychological stress. To our ...

Immunomodulatory lipid mediator profiling of cerebrospinal fluid following surgery in older adults.

Terrando, Niccolò; Park, John J; Devinney, Michael; Chan, Cliburn; Cooter, Mary; Avasarala, Pallavi; Mathew, Joseph P; ... (11 authors) (Scientific reports, 2021-02-04)

Arachidonic acid (AA), docosahexaenoic acid (DHA), and eicosapentaenoic acid (EPA) derived lipids play key roles in initiating and resolving inflammation. Neuro-inflammation is thought to play a causal role in perioperative ...

Opioid Induced Hyperalgesia

Yi, Peter

Self-system therapy for distress associated with persistent low back pain: A randomized clinical trial.

Waters, Sandra J; Strauman, Timothy J; McKee, Daphne C; Campbell, Lisa C; Shelby, Rebecca A; Dixon, Kim E; Fras, Anne Marie; ... (8 authors) (Psychother Res, 2016-07)

OBJECTIVE: Persistent low back pain (PLBP) is associated with vulnerability to depression. PLBP frequently requires major changes in occupation and lifestyle, which can lead to a sense of failing to attain one's personal ...