Browsing by Author "0136275"
Now showing items 1-10 of 10
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A branching process model for flow cytometry and budding index measurements in cell synchrony experiments.
(Ann Appl Stat, 2009)We present a flexible branching process model for cell population dynamics in synchrony/time-series experiments used to study important cellular processes. Its formulation is constructive, based on an accounting of the unique ... -
Association between DNA Damage Response and Repair Genes and Risk of Invasive Serous Ovarian Cancer
(PLOS ONE, 2010-04-08) -
Association between DNA damage response and repair genes and risk of invasive serous ovarian cancer.
(PLoS One, 2010-04-08)BACKGROUND: We analyzed the association between 53 genes related to DNA repair and p53-mediated damage response and serous ovarian cancer risk using case-control data from the North Carolina Ovarian Cancer Study (NCOCS), ... -
Bayesian Model Averaging in the M-Open Framework
(Bayesian Theory and Applications, 2013)This chapter presents a model averaging approach in the M-open setting using sample re-use methods to approximate the predictive distribution of future observations. It first reviews the standard M-closed Bayesian Model ... -
BAYESIAN MODEL SEARCH AND MULTILEVEL INFERENCE FOR SNP ASSOCIATION STUDIES.
(Ann Appl Stat, 2010-09-01)Technological advances in genotyping have given rise to hypothesis-based association studies of increasing scope. As a result, the scientific hypotheses addressed by these studies have become more complex and more difficult ... -
Expression signatures of TP53 mutations in serous ovarian cancers.
(BMC Cancer, 2010-05-26)BACKGROUND: Mutations in the TP53 gene are extremely common and occur very early in the progression of serous ovarian cancers. Gene expression patterns that relate to mutational status may provide insight into the etiology ... -
Functional annotation signatures of disease susceptibility loci improve SNP association analysis.
(BMC Genomics, 2014-05-24)BACKGROUND: Genetic association studies are conducted to discover genetic loci that contribute to an inherited trait, identify the variants behind these associations and ascertain their functional role in determining the ... -
Hosts of avian brood parasites have evolved egg signatures with elevated information content.
(Proc Biol Sci, 2015-07-07)Hosts of brood-parasitic birds must distinguish their own eggs from parasitic mimics, or pay the cost of mistakenly raising a foreign chick. Egg discrimination is easier when different host females of the same species each ... -
Risk of ovarian cancer and inherited variants in relapse-associated genes.
(PLoS One, 2010-01-27)BACKGROUND: We previously identified a panel of genes associated with outcome of ovarian cancer. The purpose of the current study was to assess whether variants in these genes correlated with ovarian cancer risk. METHODS ... -
Risk Prediction for Epithelial Ovarian Cancer in 11 United States-Based Case-Control Studies: Incorporation of Epidemiologic Risk Factors and 17 Confirmed Genetic Loci.
(Am J Epidemiol, 2016-10-15)Previously developed models for predicting absolute risk of invasive epithelial ovarian cancer have included a limited number of risk factors and have had low discriminatory power (area under the receiver operating characteristic ...
