Now showing items 1-20 of 114

    • A Foxp2 Mutation Implicated in Human Speech Deficits Alters Sequencing of Ultrasonic Vocalizations in Adult Male Mice. 

      Chabout, J; Dunson, David B; Fisher, SE; Jarvis, Erich David; Patel, SR; Radden, T; Sarkar, Abhra (Front Behav Neurosci, 2016)
      Development of proficient spoken language skills is disrupted by mutations of the FOXP2 transcription factor. A heterozygous missense mutation in the KE family causes speech apraxia, involving difficulty producing words ...
    • A framework for integrating the songbird brain. 

      Carninci, P; Dietrich, F; Hartemink, Alexander J; Hayashizaki, Y; Jarvis, Erich David; Lin, S; McConnell, P; ... (15 authors) (J Comp Physiol A Neuroethol Sens Neural Behav Physiol, 2002-12)
      Biological systems by default involve complex components with complex relationships. To decipher how biological systems work, we assume that one needs to integrate information over multiple levels of complexity. The songbird ...
    • A membrane-associated progesterone-binding protein, 25-Dx, is regulated by progesterone in brain regions involved in female reproductive behaviors. 

      Chan, Johnny; Jarvis, Erich David; Krebs, CJ; Lydon, JP; Ogawa, S; Pfaff, DW (Proc Natl Acad Sci U S A, 2000-11-07)
      The ventromedial hypothalamus (VMH) plays a central role in the regulation of the female reproductive behavior lordosis, a behavior dependent upon the sequential activation of receptors for the ovarian steroid hormones estradiol ...
    • A molecular neuroethological approach for identifying and characterizing a cascade of behaviorally regulated genes. 

      Carninci, P; Haesler, S; Hagiwara, M; Hayashizaki, Y; Hirozane-Kishikawa, T; Horita, H; Howard, JT; ... (20 authors) (Proc Natl Acad Sci U S A, 2006-10-10)
      Songbirds have one of the most accessible neural systems for the study of brain mechanisms of behavior. However, neuroethological studies in songbirds have been limited by the lack of high-throughput molecular resources ...
    • A refined model of the genomic basis for phenotypic variation in vertebrate hemostasis. 

      Bertelsen, MF; da Fonseca, RR; Gilbert, M Thomas P; Jarvis, Erich David; Kristensen, AT; Ribeiro, Ângela M; Zepeda-Mendoza, ML (BMC Evol Biol, 2015-06-30)
      BACKGROUND: Hemostasis is a defense mechanism that enhances an organism's survival by minimizing blood loss upon vascular injury. In vertebrates, hemostasis has been evolving with the cardio-vascular and hemodynamic systems ...
    • A relationship between behavior, neurotrophin expression, and new neuron survival. 

      Alvarez-Borda, B; Jarvis, Erich David; Li, XC; Lim, DA; Nottebohm, F (Proc Natl Acad Sci U S A, 2000-07-18)
      The high vocal center (HVC) controls song production in songbirds and sends a projection to the robust nucleus of the archistriatum (RA) of the descending vocal pathway. HVC receives new neurons in adulthood. Most of the ...
    • Advances to Bayesian network inference for generating causal networks from observational biological data. 

      Hartemink, Alexander J; Jarvis, Erich David; Smith, VA; Wang, PP; Yu, J (Bioinformatics, 2004-12-12)
      MOTIVATION: Network inference algorithms are powerful computational tools for identifying putative causal interactions among variables from observational data. Bayesian network inference algorithms hold particular promise ...
    • Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. 

      Adachi, J; Aizawa, K; Arakawa, T; Baldarelli, R; Batalov, S; Beisel, KW; Birney, E; ... (139 authors) (Nature, 2002-12-05)
      Only a small proportion of the mouse genome is transcribed into mature messenger RNA transcripts. There is an international collaborative effort to identify all full-length mRNA transcripts from the mouse, and to ensure ...
    • Analysis of the mouse transcriptome for genes involved in the function of the nervous system. 

      Batalov, S; Beisel, KW; Bono, H; Carninci, P; Fletcher, CF; Grimmond, S; GSL Members; ... (22 authors) (Genome Res, 2003-06)
      We analyzed the mouse Representative Transcript and Protein Set for molecules involved in brain function. We found full-length cDNAs of many known brain genes and discovered new members of known brain gene families, including ...
    • Assemblathon 2: evaluating de novo methods of genome assembly in three vertebrate species. 

      Alexandrov, A; Baranay, P; Bechner, M; Birol, I; Boisvert, S; Bradnam, KR; Chapman, JA; ... (91 authors) (Gigascience, 2013-07-22)
      BACKGROUND: The process of generating raw genome sequence data continues to become cheaper, faster, and more accurate. However, assembly of such data into high-quality, finished genome sequences remains challenging. Many ...
    • Assessing visual requirements for social context-dependent activation of the songbird song system. 

      Hara, E; Hessler, NA; Jarvis, Erich David; Kubikova, L (Proc Biol Sci, 2009-01-22)
      Social context has been shown to have a profound influence on brain activation in a wide range of vertebrate species. Best studied in songbirds, when males sing undirected song, the level of neural activity and expression ...
    • Avian brains and a new understanding of vertebrate brain evolution. 

      Avian Brain Nomenclature Consortium; Ball, GF; Bruce, Laura L; Butler, AB; Csillag, A; Dugas-Ford, J; Durand, SE; ... (30 authors) (Nat Rev Neurosci, 2005-02)
      We believe that names have a powerful influence on the experiments we do and the way in which we think. For this reason, and in the light of new evidence about the function and evolution of the vertebrate brain, an international ...
    • Avian genomes. A flock of genomes. Introduction. 

      Gilbert, M Thomas P; Jarvis, Erich David; Zhang, G (Science, 2014-12-12)
    • Avianbase: a community resource for bird genomics. 

      Aken, BL; Archibald, A; Burt, DW; Eöry, L; Flicek, P; Gilbert, M Thomas P; Jarvis, Erich David; ... (10 authors) (Genome Biol, 2015-01-29)
      Giving access to sequence and annotation data for genome assemblies is important because, while facilitating research, it places both assembly and annotation quality under scrutiny, resulting in improvements to both. Therefore ...
    • Basal ganglia function, stuttering, sequencing, and repair in adult songbirds. 

      Bosikova, E; Cvikova, M; Jarvis, Erich David; Kubikova, L; Lukacova, K; Scharff, C (Sci Rep, 2014-10-13)
      A pallial-basal-ganglia-thalamic-pallial loop in songbirds is involved in vocal motor learning. Damage to its basal ganglia part, Area X, in adult zebra finches has been noted to have no strong effects on song and its function ...
    • Behaviourally driven gene expression reveals song nuclei in hummingbird brain. 

      da Silva, ML; Jarvis, Erich David; Mello, CV; Ribeiro, S; Ventura, D; Vielliard, J (Nature, 2000-08-10)
      Hummingbirds have developed a wealth of intriguing features, such as backwards flight, ultraviolet vision, extremely high metabolic rates, nocturnal hibernation, high brain-to-body size ratio and a remarkable species-specific ...
    • Bird Brain: Evolution 

      Jarvis, Erich David (2010-12-01)
      This article presents the classic and modern views of avian brain evolution in the context of vertebrate brain evolution. The classical view held that the avian cerebrum along with those of other vertebrates evolved ...
    • Bird song systems: Evolution 

      Jarvis, Erich David (2010-12-01)
      This article presents the vocal and auditory pathways of vocal-learning birds and a hypothesis about their evolution. These pathways control the ability to produce learned song in the few groups of birds that have vocal ...
    • Birds, primates, and spoken language origins: Behavioral phenotypes and neurobiological substrates 

      Jarvis, Erich David; Petkov, CI (Frontiers in Evolutionary Neuroscience, 2012-12-01)
      Vocal learners such as humans and songbirds can learn to produce elaborate patterns of structurally organized vocalizations, whereas many other vertebrates such as non-human primates and most other bird groups either cannot ...
    • Brain evolution by brain pathway duplication. 

      Chakraborty, M; Jarvis, Erich David (Philos Trans R Soc Lond B Biol Sci, 2015-12-19)
      Understanding the mechanisms of evolution of brain pathways for complex behaviours is still in its infancy. Making further advances requires a deeper understanding of brain homologies, novelties and analogies. It also requires ...