Now showing items 1-4 of 4

    • Common genetic variation and the control of HIV-1 in humans. 

      Antonarakis, SE; Beckmann, JS; Carrington, Mary; Castagna, A; Cirulli Rogers, Elizabeth T; Colombo, S; Cozzi-Lepri, A; ... (38 authors) (PLoS Genet, 2009-12)
      To extend the understanding of host genetic determinants of HIV-1 control, we performed a genome-wide association study in a cohort of 2,554 infected Caucasian subjects. The study was powered to detect common genetic variants ...
    • Determinants of protection among HIV‐exposed seronegative persons: an overview. 

      Alter, G; Anthony, D; Carrington, Mary; Cho, M; Daskalakis, DC; Douek, DC; Goedert, JJ; ... (16 authors) (J Infect Dis, 2010-11-01)
      Both clinical experience and a growing medical literature indicate that some persons who have been exposed to human immunodeficiency virus (HIV) infection remain uninfected. Although in some instances this may represent ...
    • Host determinants of HIV-1 control in African Americans. 

      Carrington, Mary; Cronin, KD; Fellay, J; Gao, X; Ge, Dongliang; Goldstein, David Benjamin; Gumbs, Curtis E; ... (16 authors) (J Infect Dis, 2010-04-15)
      We performed a whole-genome association study of human immunodeficiency virus type 1 (HIV-1) set point among a cohort of African Americans (n = 515), and an intronic single-nucleotide polymorphism (SNP) in the HLA-B gene ...
    • Influence of HLA-C expression level on HIV control. 

      Apps, R; Bosch, R; Brumme, CJ; Brumme, ZL; Buchbinder, S; Carlson, JM; Carrington, Mary; ... (37 authors) (Science, 2013-04-05)
      A variant upstream of human leukocyte antigen C (HLA-C) shows the most significant genome-wide effect on HIV control in European Americans and is also associated with the level of HLA-C expression. We characterized ...