Now showing items 1-20 of 24

    • A polyaxonal amacrine cell population in the primate retina. 

      Field, Greg; Greschner, Martin; Li, Peter H; Schiff, Max L; Gauthier, Jeffrey L; Ahn, Daniel; Sher, Alexander; ... (9 authors) (The Journal of neuroscience : the official journal of the Society for Neuroscience, 2014-03)
      Amacrine cells are the most diverse and least understood cell class in the retina. Polyaxonal amacrine cells (PACs) are a unique subset identified by multiple long axonal processes. To explore their functional properties, ...
    • Advances in color science: From retina to behavior (The Journal of Neuroscience (2010) (14955-14963)) 

      Field, Greg; Conway, BR; Chatterjee, S; Horwitz, GD; Johnson, EN; Koida, K; Mancuso, K (Journal of Neuroscience, 2010-12-08)
    • Advances in Color Science: From Retina to Behavior (vol 30, pg 14955, 2010) 

      Field, Greg; Conway, Bevil R; Chatterjee, Soumya; Horwitz, Gregory D; Johnson, Elizabeth N; Koida, Kowa; Mancuso, Katherine (JOURNAL OF NEUROSCIENCE, 2010-12-08)
    • Advances in color science: from retina to behavior. 

      Johnson, Elizabeth; Field, Greg; Conway, Bevil R; Chatterjee, Soumya; Horwitz, Gregory D; Koida, Kowa; Mancuso, Katherine (The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010-11)
      Color has become a premier model system for understanding how information is processed by neural circuits, and for investigating the relationships among genes, neural circuits, and perception. Both the physical stimulus ...
    • Anatomical identification of extracellularly recorded cells in large-scale multielectrode recordings. 

      Ahn, D; Callaway, EM; Chichilnisky, EJ; Field, Greg; Gauthier, JL; Greschner, M; Li, PH; ... (10 authors) (J Neurosci, 2015-03-18)
      This study combines for the first time two major approaches to understanding the function and structure of neural circuits: large-scale multielectrode recordings, and confocal imaging of labeled neurons. To achieve this ...
    • Behavioural and physiological limits to vision in mammals. 

      Field, Greg; Sampath, Alapakkam P (Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2017-04)
      Human vision is exquisitely sensitive-a dark-adapted observer is capable of reliably detecting the absorption of a few quanta of light. Such sensitivity requires that the sensory receptors of the retina, rod photoreceptors, ...
    • Cell type-specific changes in retinal ganglion cell function induced by rod death and cone reorganization in rats. 

      Field, Greg; Yu, Wan-Qing; Grzywacz, Norberto M; Lee, Eun-Jin (Journal of neurophysiology, 2017-07)
      We have determined the impact of rod death and cone reorganization on the spatiotemporal receptive fields (RFs) and spontaneous activity of distinct retinal ganglion cell (RGC) types. We compared RGC function between healthy ...
    • Correlated firing among major ganglion cell types in primate retina. 

      Field, Greg; Greschner, Martin; Shlens, Jonathon; Bakolitsa, Constantina; Gauthier, Jeffrey L; Jepson, Lauren H; Sher, Alexander; ... (9 authors) (The Journal of physiology, 2011-01)
      Retinal ganglion cells exhibit substantial correlated firing: a tendency to fire nearly synchronously at rates different from those expected by chance. These correlations suggest that network interactions significantly shape ...
    • Distribution and diversity of intrinsically photosensitive retinal ganglion cells in tree shrew. 

      Johnson, Elizabeth; Field, Greg; Westbrook, Teleza; Shayesteh, Rod; Chen, Emily L; Schumacher, Joseph W; Fitzpatrick, David (The Journal of comparative neurology, 2017-12-14)
      Intrinsically photosensitive retinal ganglion cells (ipRGCs) mediate the pupillary light reflex, circadian entrainment, and may contribute to luminance and color perception. The diversity of ipRGCs varies from rodents to ...
    • Efficient coding of spatial information in the primate retina. 

      Field, Greg; Doi, Eizaburo; Gauthier, Jeffrey L; Shlens, Jonathon; Sher, Alexander; Greschner, Martin; Machado, Timothy A; ... (14 authors) (The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012-11)
      Sensory neurons have been hypothesized to efficiently encode signals from the natural environment subject to resource constraints. The predictions of this efficient coding hypothesis regarding the spatial filtering properties ...
    • Formation of retinal direction-selective circuitry initiated by starburst amacrine cell homotypic contact. 

      Field, Greg; Kay, Jeremy; Ray, Thomas A; Roy, Suva; Kozlowski, Christopher; Wang, Jingjing; Cafaro, Jon; ... (9 authors) (eLife, 2018-04-03)
      A common strategy by which developing neurons locate their synaptic partners is through projections to circuit-specific neuropil sublayers. Once established, sublayers serve as a substrate for selective synapse formation, ...
    • Functional connectivity in the retina at the resolution of photoreceptors. 

      Field, Greg; Gauthier, Jeffrey L; Sher, Alexander; Greschner, Martin; Machado, Timothy A; Jepson, Lauren H; Shlens, Jonathon; ... (13 authors) (Nature, 2010-10)
      To understand a neural circuit requires knowledge of its connectivity. Here we report measurements of functional connectivity between the input and ouput layers of the macaque retina at single-cell resolution and the implications ...
    • Gap Junctions Contribute to Differential Light Adaptation across Direction-Selective Retinal Ganglion Cells. 

      Field, Greg; Yao, Xiaoyang; Cafaro, Jon; McLaughlin, Amanda J; Postma, Friso R; Paul, David L; Awatramani, Gautam (Neuron, 2018-10)
      Direction-selective ganglion cells (DSGCs) deliver signals from the retina to multiple brain areas to indicate the presence and direction of motion. Delivering reliable signals in response to motion is critical across light ...
    • High-sensitivity rod photoreceptor input to the blue-yellow color opponent pathway in macaque retina. 

      Chichilnisky, EJ; Field, Greg; Gauthier, JL; Greschner, M; Litke, Alan M; Marshak, DW; Rangel, C; ... (9 authors) (Nat Neurosci, 2009-09)
      Small bistratified cells (SBCs) in the primate retina carry a major blue-yellow opponent signal to the brain. We found that SBCs also carry signals from rod photoreceptors, with the same sign as S cone input. SBCs exhibited ...
    • Identification of a Retinal Circuit for Recurrent Suppression Using Indirect Electrical Imaging. 

      Field, Greg; Greschner, Martin; Heitman, Alexander K; Li, Peter H; Ahn, Daniel; Sher, Alexander; Litke, Alan M; ... (8 authors) (Current biology : CB, 2016-08)
      Understanding the function of modulatory interneuron networks is a major challenge, because such networks typically operate over long spatial scales and involve many neurons of different types. Here, we use an indirect electrical ...
    • Mapping nonlinear receptive field structure in primate retina at single cone resolution. 

      Field, Greg; Freeman, Jeremy; Li, Peter H; Greschner, Martin; Gunning, Deborah E; Mathieson, Keith; Sher, Alexander; ... (11 authors) (eLife, 2015-10-30)
      The function of a neural circuit is shaped by the computations performed by its interneurons, which in many cases are not easily accessible to experimental investigation. Here, we elucidate the transformation of visual signals ...
    • Monte Carlo methods for localization of cones given multielectrode retinal ganglion cell recordings. 

      Field, Greg; Sadeghi, K; Gauthier, JL; Greschner, M; Agne, M; Chichilnisky, EJ; Paninski, L (Network (Bristol, England), 2013-01)
      It has recently become possible to identify cone photoreceptors in primate retina from multi-electrode recordings of ganglion cell spiking driven by visual stimuli of sufficiently high spatial resolution. In this paper we ...
    • Nogo receptor 1 is expressed by nearly all retinal ganglion cells. 

      Field, Greg; Solomon, Alexander M; Westbrook, Teleza; McGee, Aaron W (PloS one, 2018-01)
      A variety of conditions ranging from glaucoma to blunt force trauma lead to optic nerve atrophy. Identifying signaling pathways for stimulating axon growth in the optic nerve may lead to treatments for these pathologies. ...
    • Optimal processing of photoreceptor signals is required to maximize behavioural sensitivity. 

      Field, Greg; Okawa, Haruhisa; Miyagishima, K Joshua; Arman, A Cyrus; Hurley, James B; Sampath, Alapakkam P (The Journal of physiology, 2010-06)
      The sensitivity of receptor cells places a fundamental limit upon the sensitivity of sensory systems. For example, the signal-to-noise ratio of sensory receptors has been suggested to limit absolute thresholds in the visual ...
    • Probing Computation in the Primate Visual System at Single-Cone Resolution. 

      Field, Greg; Kling, A; Brainard, DH; Chichilnisky, EJ (Annual review of neuroscience, 2019-03-11)
      Daylight vision begins when light activates cone photoreceptors in the retina, creating spatial patterns of neural activity. These cone signals are then combined and processed in downstream neural circuits, ultimately producing ...