Browsing by Author "Abraham, Soman N"
Now showing items 1-6 of 6
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Contributions of mast cells and vasoactive products, leukotrienes and chymase, to dengue virus-induced vascular leakage.
(Elife, 2013-04-30)Dengue Virus (DENV), a flavivirus spread by mosquito vectors, can cause vascular leakage and hemorrhaging. However, the processes that underlie increased vascular permeability and pathological plasma leakage during viral ... -
IL-27 Facilitates Skin Wound Healing through Induction of Epidermal Proliferation and Host Defense.
(The Journal of investigative dermatology, 2017-05)Skin wound repair requires a coordinated program of epithelial cell proliferation and differentiation as well as resistance to invading microbes. However, the factors that trigger epithelial cell proliferation in ... -
MRGPR-mediated activation of local mast cells clears cutaneous bacterial infection and protects against reinfection.
(Science advances, 2019-01-02)Mast cells (MCs) are strategically distributed at barrier sites and prestore various immunocyte-recruiting cytokines, making them ideal targets for selective activation to treat peripheral infections. Here, we report that ... -
Novel mucosal adjuvant, mastoparan-7, improves cocaine vaccine efficacy
(npj Vaccines, 2020-12) -
Role of mast cells in inflammatory bowel disease and inflammation-associated colorectal neoplasia in IL-10-deficient mice.
(PLoS One, 2010-08-17)BACKGROUND: Inflammatory bowel disease (IBD) is hypothesized to result from stimulation of immune responses against resident intestinal bacteria within a genetically susceptible host. Mast cells may play a critical role ... -
Why Serological Responses during Cystitis are Limited.
(Pathogens, 2016-02-14)The high frequency of urinary tract infections (UTIs), some of which appear to be endogenous relapses rather than reinfections by new isolates, point to defects in the host's memory immune response. It has been known for ...
