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Browsing by Author "Alexander, BD"

Now showing items 1-7 of 7

    • Cytokine gene polymorphisms and the outcome of invasive candidiasis: a prospective cohort study. 

      Johnson, MD; Plantinga, TS; van de Vosse, E; Velez Edwards, DR; Smith, PB; Alexander, BD; Yang, JC; ... (18 authors) (Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2012-02)
      BACKGROUND:  Candida bloodstream infections cause significant morbidity and mortality among hospitalized patients. Although clinical and microbiological factors affecting prognosis have been identified, the impact of genetic ...

    • Evaluation of a digital microfluidic real-time PCR platform to detect DNA of Candida albicans in blood. 

      Schell, WA; Benton, JL; Smith, PB; Poore, M; Rouse, JL; Boles, DJ; Johnson, MD; ... (14 authors) (Eur J Clin Microbiol Infect Dis, 2012-09)
      Species of Candida frequently cause life-threatening infections in neonates, transplant and intensive care unit (ICU) patients, and others with compromised host defenses. The successful management of systemic candidiasis ...

    • Hemorrhagic Herpes Simplex Virus Type 1 Nephritis: An Unusual Cause of Acute Allograft Dysfunction. 

      Hemmersbach-Miller, M; Duronville, J; Sethi, S; Miller, SE; Howell, DN; Henshaw, N; Alexander, BD; ... (8 authors) (Am J Transplant, 2017-01)
      Interstitial nephritis due to viruses is well-described after solid organ transplantation. Viruses implicated include cytomegalovirus; BK polyomavirus; Epstein-Barr virus; and, less commonly, adenovirus. We describe a rare ...

    • Multicenter Registry of Patients Receiving Systemic Mold-Active Triazoles for the Management of Invasive Fungal Infections. 

      Ostrosky-Zeichner, L; Nguyen, MH; Bubalo, J; Alexander, BD; Miceli, MH; Pappas, PG; Jiang, J; ... (9 authors) (Infectious diseases and therapy, 2022-08)
      <h4>Introduction</h4>'Real-world' data for mold-active triazoles (MATs) in the treatment of invasive fungal infections (IFIs) are lacking. This study evaluated usage of MATs in a disease registry for the management ...

    • Prevalence of renal anomalies after urinary tract infections in hospitalized infants less than 2 months of age. 

      Nowell, L; Moran, C; Smith, PB; Seed, P; Alexander, BD; Cotten, CM; Wiener, JS; ... (8 authors) (J Perinatol, 2010-04)
      OBJECTIVE: Our aim was to determine the incidence of anatomical abnormalities after a urinary tract infection (UTI) in infants <2 months of age hospitalized in the neonatal intensive care unit (NICU). STUDY DESIGN: This ...

    • The impact of caspase-12 on susceptibility to candidemia. 

      Rosentul, DC; Plantinga, TS; Scott, WK; Alexander, BD; van de Geer, NMD; Perfect, JR; Kullberg, BJ; ... (9 authors) (European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2012-03)
      Candida is one of the leading causes of sepsis, and an effective host immune response to Candida critically depends on the cytokines IL-1β and IL-18, which need caspase-1 cleavage to become bioactive. Caspase-12 has been ...

    • Unrecognized pretransplant and donor‐derived cryptococcal disease in organ transplant recipients. 

      Sun, HY; Alexander, BD; Lortholary, O; Dromer, F; Forrest, GN; Lyon, GM; Somani, J; ... (34 authors) (Clin Infect Dis, 2010-11-01)
      BACKGROUND: Cryptococcosis occurring ≤30 days after transplantation is an unusual event, and its characteristics are not known. METHODS: Patients included 175 solid-organ transplant (SOT) recipients with cryptococcosis in ...