Browsing by Author "Altan, Irem"
Now showing items 1-8 of 8
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Computational crystallization.
(Arch Biochem Biophys, 2016-07-15)Crystallization is a key step in macromolecular structure determination by crystallography. While a robust theoretical treatment of the process is available, due to the complexity of the system, the experimental process ... -
Correction to: Obtaining Soft Matter Models of Proteins and their Phase Behavior.
(Methods in molecular biology (Clifton, N.J.), 2019-01)The acknowledgement section text has been updated in the chapter. -
Learning about Biomolecular Solvation from Water in Protein Crystals.
(The journal of physical chemistry. B, 2018-03)Water occupies typically 50% of a protein crystal and thus significantly contributes to the diffraction signal in crystallography experiments. Separating its contribution from that of the protein is, however, challenging ... -
Obtaining Soft Matter Models of Proteins and their Phase Behavior.
(Methods in molecular biology (Clifton, N.J.), 2019-01)Globular proteins are roughly spherical biomolecules with attractive and highly directional interactions. This microscopic observation motivates describing these proteins as patchy particles: hard spheres with attractive ... -
Sugars: Soft Caramel and Sucre à la Crème--an Undergraduate Experiment about Sugar Crystallization
(2021)A comprehensive reference to molecular gastronomy, this book highlights techniques that have enabled chefs to achieve new and better ways of preparing food. -
Temperature-dependent non-covalent protein-protein interactions explain normal and inverted solubility in a mutant of human gamma D-crystallin
Protein crystal production is a major bottleneck for the structural characterisation of proteins. To advance beyond large-scale screening, rational strategies for protein crystallization are crucial. Understanding ... -
Understanding the Structure and Formation of Protein Crystals Using Computer Simulation and Theory
(2019)The complexity of protein-protein interactions enables proteins to self-assemble into a rich array of structures, such as virus capsids, amyloid fibers, amorphous aggregates, and protein crystals. While some of these assemblies ... -
Using Schematic Models to Understand the Microscopic Basis for Inverted Solubility in γD-Crystallin.
(The journal of physical chemistry. B, 2019-11)Inverted solubility-melting a crystal by cooling-is observed in a handful of proteins, such as carbomonoxy hemoglobin C and γD-crystallin. In human γD-crystallin, the phenomenon is associated with the mutation of the 23rd ...
