Now showing items 1-4 of 4

    • Generalized admixture mapping for complex traits. 

      Zhu, Bin; Ashley-Koch, Allison E; Dunson, David B (G3 (Bethesda), 2013-07-08)
      Admixture mapping is a popular tool to identify regions of the genome associated with traits in a recently admixed population. Existing methods have been developed primarily for identification of a single locus influencing ...
    • In vivo Modeling Implicates APOL1 in Nephropathy: Evidence for Dominant Negative Effects and Epistasis under Anemic Stress. 

      Anderson, Blair R; Howell, David N; Soldano, Karen; Garrett, Melanie E; Katsanis, Nicholas; Telen, Marilyn J; Davis, Erica E; ... (8 authors) (PLoS Genet, 2015-07)
      African Americans have a disproportionate risk for developing nephropathy. This disparity has been attributed to coding variants (G1 and G2) in apolipoprotein L1 (APOL1); however, there is little functional evidence supporting ...
    • Joint eQTL assessment of whole blood and dura mater tissue from individuals with Chiari type I malformation. 

      Lock, Eric F; Soldano, Karen L; Garrett, Melanie E; Cope, Heidi; Markunas, Christina A; Fuchs, Herbert; Grant, Gerald; ... (10 authors) (BMC Genomics, 2015-01-22)
      BACKGROUND: Expression quantitative trait loci (eQTL) play an important role in the regulation of gene expression. Gene expression levels and eQTLs are expected to vary from tissue to tissue, and therefore multi-tissue analyses ...
    • The PsychENCODE project. 

      PsychENCODE Consortium; Akbarian, Schahram; Liu, Chunyu; Knowles, James A; Vaccarino, Flora M; Farnham, Peggy J; Crawford, Gregory E; ... (86 authors) (Nat Neurosci, 2015-12)