Now showing items 1-2 of 2

    • High Multiplicity Infection by HIV-1 in Men Who Have Sex with Men. 

      al, E; Bar, KJ; Chen, Y; Decker, JM; Learn, Gerald H; Li, H; Morgan, CJ; ... (11 authors) (PLoS pathogens, 2010)
      Elucidating virus-host interactions responsible for HIV-1 transmission is important for advancing HIV-1 prevention strategies. To this end, single genome amplification (SGA) and sequencing of HIV-1 within the context of ...
    • Initial antibodies binding to HIV-1 gp41 in acutely infected subjects are polyreactive and highly mutated. 

      Alam, S Munir; Bar, KJ; Boyd, SD; Chen, X; Denny, Thomas Norton; Egholm, M; Fire, AZ; ... (32 authors) (J Exp Med, 2011-10-24)
      The initial antibody response to HIV-1 is targeted to envelope (Env) gp41, and is nonneutralizing and ineffective in controlling viremia. To understand the origins and characteristics of gp41-binding antibodies produced ...