Browsing by Author "Beaumont, Tim"

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    • CD20 deficiency in humans results in impaired T cell-independent antibody responses. 

      Kuijpers, Taco W; Bende, Richard J; Baars, Paul A; Grummels, Annette; Derks, Ingrid AM; Dolman, Koert M; Beaumont, Tim; ... (11 authors) (J Clin Invest, 2010-01)
      CD20 was the first B cell differentiation antigen identified, and CD20-specific mAbs are commonly used for the treatment of B cell malignancies and autoantibody-mediated autoimmune diseases. Despite this the role of CD20 ...