Now showing items 1-2 of 2

    • Distinct routes to metastasis: plasticity-dependent and plasticity-independent pathways. 

      Armstrong, AJ; Bepler, T; Buckley, Anne Frances; Epstein, JI; Garcia-Blanco, Mariano Agustin; Hish, AJ; Marengo, MS; ... (13 authors) (Oncogene, 2016-08-18)
      The cascade that culminates in macrometastases is thought to be mediated by phenotypic plasticity, including epithelial-mesenchymal and mesenchymal-epithelial transitions (EMT and MET). Although there is substantial support ...
    • Human-chimpanzee differences in a FZD8 enhancer alter cell-cycle dynamics in the developing neocortex. 

      Bepler, T; Boyd, J Lomax; Gordân, R; Pilaz, LJ; Rouanet, JP; Silver, Debra Lynn; Skove, SL; ... (8 authors) (Curr Biol, 2015-03-16)
      The human neocortex differs from that of other great apes in several notable regards, including altered cell cycle, prolonged corticogenesis, and increased size [1-5]. Although these evolutionary changes most likely contributed ...