Browsing by Author "Bodinayake, Champica K"
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Antibiotic overuse for acute respiratory tract infections in Sri Lanka: a qualitative study of outpatients and their physicians.
Tillekeratne, L Gayani; Bodinayake, Champica K; Dabrera, Thushani; Nagahawatte, Ajith; Arachchi, Wasantha Kodikara; Sooriyaarachchi, Anoji; Stewart, Kearsley; ... (10 authors) (BMC Fam Pract, 2018-03-01)BACKGROUND: Acute respiratory tract infections (ARTIs) are a common reason for antibiotic overuse worldwide. We previously showed that over 80% of outpatients presenting to a tertiary care hospital in Sri Lanka ... -
Emergence of Epidemic Dengue-1 Virus in the Southern Province of Sri Lanka.
Bodinayake, Champica K; Tillekeratne, L Gayani; Nagahawatte, Ajith; Devasiri, Vasantha; Kodikara Arachichi, Wasantha; Strouse, John J; Sessions, October M; ... (19 authors) (PLoS Negl Trop Dis, 2016-10)BACKGROUND: Dengue is a frequent cause of acute febrile illness with an expanding global distribution. Since the 1960s, dengue in Sri Lanka has been documented primarily along the heavily urbanized western coast with periodic ... -
Previously Derived Host Gene Expression Classifiers Identify Bacterial and Viral Etiologies of Acute Febrile Respiratory Illness in a South Asian Population.
Tillekeratne, L Gayani; Suchindran, Sunil; Ko, Emily R; Petzold, Elizabeth A; Bodinayake, Champica K; Nagahawatte, Ajith; Devasiri, Vasantha; ... (16 authors) (Open forum infectious diseases, 2020-06)Background:Pathogen-based diagnostics for acute respiratory infection (ARI) have limited ability to detect etiology of illness. We previously showed that peripheral blood-based host gene expression classifiers accurately ... -
The Host Response to Viral Infections Reveals Common and Virus-Specific Signatures in the Peripheral Blood.
Tsalik, Ephraim L; Fiorino, Cassandra; Aqeel, Ammara; Liu, Yiling; Henao, Ricardo; Ko, Emily R; Burke, Thomas W; ... (18 authors) (Frontiers in immunology, 2021-01)Viruses cause a wide spectrum of clinical disease, the majority being acute respiratory infections (ARI). In most cases, ARI symptoms are similar for different viruses although severity can be variable. The objective of ...