Now showing items 1-2 of 2

    • Plasticity of Hopx(+) type I alveolar cells to regenerate type II cells in the lung. 

      Jain, Rajan; Barkauskas, Christina E; Takeda, Norifumi; Bowie, Emily J; Aghajanian, Haig; Wang, Qiaohong; Padmanabhan, Arun; ... (14 authors) (Nature communications, 2015-04-13)
      The plasticity of differentiated cells in adult tissues undergoing repair is an area of intense research. Pulmonary alveolar type II cells produce surfactant and function as progenitors in the adult, demonstrating ...
    • Type 2 alveolar cells are stem cells in adult lung. 

      Barkauskas, Christina E; Cronce, Michael J; Rackley, Craig R; Bowie, Emily J; Keene, Douglas R; Stripp, Barry R; Randell, Scott H; ... (9 authors) (The Journal of clinical investigation, 2013-07)
      Gas exchange in the lung occurs within alveoli, air-filled sacs composed of type 2 and type 1 epithelial cells (AEC2s and AEC1s), capillaries, and various resident mesenchymal cells. Here, we use a combination of in vivo ...