Now showing items 1-3 of 3

    • A chemical glycoproteomics platform reveals O-GlcNAcylation of mitochondrial voltage-dependent anion channel 2. 

      Palaniappan, K; Hangauer, M; Smith, T; Smart, B; Pitcher, A; Cheng, E; Bertozzi, C; ... (8 authors) (Cell Rep, 2013-10-31)
      Protein modification by O-linked β-N-acetylglucosamine (O-GlcNAc) is a critical cell signaling modality, but identifying signal-specific O-GlcNAcylation events remains a significant experimental challenge. Here, we describe ...
    • Caspases: an ancient cellular sword of Damocles. 

      Boyce, M; Degterev, A; Yuan, J (Cell death and differentiation, 2004-01)
      Caspases are a family of cysteine proteases homologous to the Caenorhabditis elegans programmed cell death gene product CED-3. Caspases and their distant relatives, meta- and paracaspases, have been found in phylogenetically ...
    • The channel of death. 

      Degterev, A; Boyce, M; Yuan, J (The Journal of cell biology, 2001-11-26)
      The proapoptotic members of the Bcl-2 family have been proposed to participate in the formation of a channel that releases these apoptogenic factors when mitochondria receive apoptotic signals. A recent study provides the ...