Browsing by Author "Boyle, Jon P"
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A three-dimensional culture system recapitulates placental syncytiotrophoblast development and microbial resistance.
McConkey, Cameron A; Delorme-Axford, Elizabeth; Nickerson, Cheryl A; Kim, Kwang Sik; Sadovsky, Yoel; Boyle, Jon P; Coyne, Carolyn B (Science advances, 2016-03-04)In eutherians, the placenta acts as a barrier and conduit at the maternal-fetal interface. Syncytiotrophoblasts, the multinucleated cells that cover the placental villous tree surfaces of the human placenta, are directly ... -
Cell type- and species-specific host responses to Toxoplasma gondii and its near relatives.
Wong, Zhee S; Borrelli, Sarah L Sokol; Coyne, Carolyn C; Boyle, Jon P (International journal for parasitology, 2020-05-11)Toxoplasma gondii is remarkably unique in its ability to successfully infect vertebrate hosts from multiple phyla and can successfully infect most cells within these organisms. The infection outcome in each of these species ...