Browsing by Author "Chamessian, Alexander"
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Differential expression of systemic inflammatory mediators in amputees with chronic residual limb pain.
Chamessian, Alexander; Van de Ven, Thomas; Buchheit, Thomas; Hsia, Hung-Lun; McDuffie, Mary; Gamazon, Eric R; Walsh, Colin; ... (10 authors) (Pain, 2017-01)Chronic postsurgical pain impacts most amputees, with more than half experiencing neuralgic residual limb pain. The transition from normal acute postamputation pain to chronic residual limb pain likely involves both peripheral ... -
Pain Phenotypes and Associated Clinical Risk Factors Following Traumatic Amputation: Results from Veterans Integrated Pain Evaluation Research (VIPER).
Buchheit, Thomas; Van de Ven, Thomas; Hsia, Hung-Lun John; McDuffie, Mary; MacLeod, David B; White, William; Chamessian, Alexander; ... (10 authors) (Pain medicine (Malden, Mass.), 2016-01)OBJECTIVE:To define clinical phenotypes of postamputation pain and identify markers of risk for the development of chronic pain. DESIGN:Cross-sectional study of military service members enrolled 3-18 months after traumatic ... -
Pain regulation by non-neuronal cells and inflammation.
Ji, Ru-Rong; Chamessian, Alexander; Zhang, Yu-Qiu (Science, 2016-11-04)Acute pain is protective and a cardinal feature of inflammation. Chronic pain after arthritis, nerve injury, cancer, and chemotherapy is associated with chronic neuroinflammation, a local inflammation in the peripheral or ... -
The Cellular Determinants of Spinal and Peripheral Pain Processing
Chamessian, Alexander (2018)Chronic pain is a major public health issue, affecting over 100 million people in costing over $600 million annually in the United States. The lack of effective therapies for chronic pain have directly contributed to the ...