Browsing by Author "Cyr, Derek D"
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Dusp3 and Psme3 are associated with murine susceptibility to Staphylococcus aureus infection and human sepsis.
Yan, Qin; Sharma-Kuinkel, Batu K; Deshmukh, Hitesh; Tsalik, Ephraim L; Cyr, Derek D; Lucas, Joseph; Woods, Christopher W; ... (13 authors) (PLoS Pathog, 2014-06)Using A/J mice, which are susceptible to Staphylococcus aureus, we sought to identify genetic determinants of susceptibility to S. aureus, and evaluate their function with regard to S. aureus infection. One QTL region on ... -
Gene Expression Profiles Link Respiratory Viral Infection, Platelet Response to Aspirin, and Acute Myocardial Infarction.
Rose, Jason J; Voora, Deepak; Cyr, Derek D; Lucas, Joseph E; Zaas, Aimee K; Woods, Christopher W; Newby, L Kristin; ... (9 authors) (PLoS One, 2015)BACKGROUND: Influenza infection is associated with myocardial infarction (MI), suggesting that respiratory viral infection may induce biologic pathways that contribute to MI. We tested the hypotheses that 1) a validated ... -
Gene expression-based classifiers identify Staphylococcus aureus infection in mice and humans.
Ahn, Sun Hee; Tsalik, Ephraim L; Cyr, Derek D; Zhang, Yurong; van Velkinburgh, Jennifer C; Langley, Raymond J; Glickman, Seth W; ... (18 authors) (PLoS One, 2013)Staphylococcus aureus causes a spectrum of human infection. Diagnostic delays and uncertainty lead to treatment delays and inappropriate antibiotic use. A growing literature suggests the host's inflammatory response to the ... -
The Risk of Cardiac Device-Related Infection in Bacteremic Patients Is Species Specific: Results of a 12-Year Prospective Cohort.
Maskarinec, Stacey A; Thaden, Joshua T; Cyr, Derek D; Ruffin, Felicia; Souli, Maria; Fowler, Vance G (Open forum infectious diseases, 2017-01)The species-specific risk of cardiac device-related infection (CDRI) among bacteremic patients is incompletely understood.We conducted a prospective cohort study of hospitalized patients from October 2002 to December 2014 ...