Browsing by Author "Dawson, Hana N"
Now showing items 1-3 of 3
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Anti-inflammatory effects of progesterone in lipopolysaccharide-stimulated BV-2 microglia.
Lei, Beilei; Mace, Brian; Dawson, Hana N; Warner, David S; Laskowitz, Daniel T; James, Michael L (PLoS One, 2014)Female sex is associated with improved outcome in experimental brain injury models, such as traumatic brain injury, ischemic stroke, and intracerebral hemorrhage. This implies female gonadal steroids may be neuroprotective. ... -
Traumatic brain injury exacerbates neurodegenerative pathology: improvement with an apolipoprotein E-based therapeutic.
Laskowitz, Daniel T; Song, Pingping; Wang, Haichen; Mace, Brian; Sullivan, Patrick M; Vitek, Michael P; Dawson, Hana N (J Neurotrauma, 2010-11)Cognitive impairment is common following traumatic brain injury (TBI), and neuroinflammatory mechanisms may predispose to the development of neurodegenerative disease. Apolipoprotein E (apoE) polymorphisms modify ... -
Tumor necrosis factor α antagonism improves neurological recovery in murine intracerebral hemorrhage.
Lei, Beilei; Dawson, Hana N; Roulhac-Wilson, Briana; Wang, Haichen; Laskowitz, Daniel T; James, Michael L (J Neuroinflammation, 2013-08-20)BACKGROUND: Intracerebral hemorrhage (ICH) is a devastating stroke subtype characterized by a prominent neuroinflammatory response. Antagonism of pro-inflammatory cytokines by specific antibodies represents a compelling ...