Browsing by Author "Delorme-Axford, Elizabeth"
Now showing items 1-3 of 3
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A three-dimensional culture system recapitulates placental syncytiotrophoblast development and microbial resistance.
(Science advances, 2016-03-04)In eutherians, the placenta acts as a barrier and conduit at the maternal-fetal interface. Syncytiotrophoblasts, the multinucleated cells that cover the placental villous tree surfaces of the human placenta, are directly ... -
BPIFB3 regulates autophagy and coxsackievirus B replication through a noncanonical pathway independent of the core initiation machinery.
(mBio, 2014-12-09)<h4>Unlabelled</h4>Enteroviruses require autophagy to facilitate the formation of autophagosome (AP)-like double-membrane vesicles that provide the scaffolding for RNA replication. Here, we identify bactericidal/permeabi... -
The actin cytoskeleton as a barrier to virus infection of polarized epithelial cells.
(Viruses, 2011-12-21)Many diverse viruses target a polarized epithelial monolayer during host invasion. The polarized epithelium is adept at restricting the movement of solutes, ions, macromolecules, and pathogens across the mucosa. This regulation ...
