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Browsing by Author "Doraiswamy, P Murali"
Now showing items 1-8 of 8
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Accelerating stem cell trials for Alzheimer's disease.
(The Lancet. Neurology, 2016-02)At present, no effective cure or prophylaxis exists for Alzheimer's disease. Symptomatic treatments are modestly effective and offer only temporary benefit. Advances in induced pluripotent stem cell (iPSC) technology have ... -
Altered bile acid profile associates with cognitive impairment in Alzheimer's disease-An emerging role for gut microbiome.
(Alzheimer's & dementia : the journal of the Alzheimer's Association, 2018-10-08)INTRODUCTION:Increasing evidence suggests a role for the gut microbiome in central nervous system disorders and a specific role for the gut-brain axis in neurodegeneration. Bile acids (BAs), products of cholesterol metabolism ... -
Assessment of the Feasibility of Using Noninvasive Wearable Biometric Monitoring Sensors to Detect Influenza and the Common Cold Before Symptom Onset.
(JAMA network open, 2021-09)<h4>Importance</h4>Currently, there are no presymptomatic screening methods to identify individuals infected with a respiratory virus to prevent disease spread and to predict their trajectory for resource allocation.<h4>... -
Association of Altered Liver Enzymes With Alzheimer Disease Diagnosis, Cognition, Neuroimaging Measures, and Cerebrospinal Fluid Biomarkers.
(JAMA network open, 2019-07-03)Importance:Increasing evidence suggests an important role of liver function in the pathophysiology of Alzheimer disease (AD). The liver is a major metabolic hub; therefore, investigating the association of liver function ... -
Cortical β-amyloid levels and neurocognitive performance after cardiac surgery.
(BMJ Open, 2013-09-20)INTRODUCTION: Neurological and neurocognitive dysfunction occurs frequently in the large number of increasingly elderly patients undergoing cardiac surgery every year. Perioperative cognitive deficits have been shown to ... -
Evaluating Alzheimer Disease With Flortaucipir and Florbetapir PET: A Clinical Case Series.
(Clinical nuclear medicine, 2021-07)<h4>Abstract</h4>Early, accurate diagnosis of Alzheimer disease (AD) is essential but remains challenging. Neuropathological hallmarks of AD are β-amyloid neuritic plaques and tau protein neurofibrillary tangles. 18F-Florbetapir ... -
Neuroimaging assessment of early and late neurobiological sequelae of traumatic brain injury: implications for CTE.
(Front Neurosci, 2015)Traumatic brain injury (TBI) has been increasingly accepted as a major external risk factor for neurodegenerative morbidity and mortality. Recent evidence indicates that the resultant chronic neurobiological sequelae following ... -
PET Imaging of Tau Pathology in Alzheimer's Disease and Tauopathies.
(Frontiers in neurology, 2015-01)
