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Browsing by Author "Eward, William C"
Now showing items 1-8 of 8
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A Fluorescence-Guided Laser Ablation System for Removal of Residual Cancer in a Mouse Model of Soft Tissue Sarcoma.
Lazarides, Alexander L; Whitley, Melodi J; Strasfeld, David B; Cardona, Diana M; Ferrer, Jorge M; Mueller, Jenna L; Fu, Henry L; ... (12 authors) (Theranostics, 2016)The treatment of soft tissue sarcoma (STS) generally involves tumor excision with a wide margin. Although advances in fluorescence imaging make real-time detection of cancer possible, removal is limited by the precision ... -
Extirpative cultures reveal infectious pubic bone osteomyelitis in prostate cancer survivors with urinary-pubic symphysis fistulae (UPF).
Nosé, Brent D; Boysen, William R; Kahokehr, Arman A; Inouye, Brian M; Eward, William C; Hendershot, Edward F; Peterson, Andrew C (Urology, 2020-05-07)OBJECTIVE:To examine the infectious features of patients with urinary pubic symphysis fistula (UPF) and their association with osteomyelitis. METHODS:We conducted a review of our quality improvement database for 36 patients ... -
Genetic determinants of childhood and adult height associated with osteosarcoma risk.
Zhang, Chenan; Morimoto, Libby M; de Smith, Adam J; Hansen, Helen M; Gonzalez-Maya, Julio; Endicott, Alyson A; Smirnov, Ivan V; ... (12 authors) (Cancer, 2018-09)BACKGROUND:Although increased height has been associated with osteosarcoma risk in previous epidemiologic studies, to the authors' knowledge the relative contribution of stature during different developmental timepoints ... -
Mesenchymal-Epithelial Transition in Sarcomas Is Controlled by the Combinatorial Expression of MicroRNA 200s and GRHL2.
Somarelli, Jason A; Shetler, Samantha; Jolly, Mohit K; Wang, Xueyang; Bartholf Dewitt, Suzanne; Hish, Alexander J; Gilja, Shivee; ... (12 authors) (Mol Cell Biol, 2016-10-01)Phenotypic plasticity involves a process in which cells transiently acquire phenotypic traits of another lineage. Two commonly studied types of phenotypic plasticity are epithelial-mesenchymal transition (EMT) and ... -
Preclinical Testing of a Novel Niclosamide Stearate Prodrug Therapeutic (NSPT) Shows Efficacy Against Osteosarcoma.
Reddy, Gireesh B; Kerr, David L; Spasojevic, Ivan; Tovmasyan, Artak; Hsu, David S; Brigman, Brian E; Somarelli, Jason A; ... (9 authors) (Molecular cancer therapeutics, 2020-07)Therapeutic advances for osteosarcoma have stagnated over the past several decades, leading to an unmet clinical need for patients. The purpose of this study was to develop a novel therapy for osteosarcoma by reformulating ... -
Pseudotumor with superimposed periprosthetic infection following metal-on-metal total hip arthroplasty: a case report.
Watters, Tyler Steven; Eward, William C; Hallows, Rhett K; Dodd, Leslie G; Wellman, Samuel S; Bolognesi, Michael P (J Bone Joint Surg Am, 2010-07-07) -
The vascularized fibular graft in the pediatric upper extremity: a durable, biological solution to large oncologic defects.
Zelenski, Nicki; Brigman, Brian E; Levin, L Scott; Erdmann, Detlev; Eward, William C (Sarcoma, 2013-01)Skeletal reconstruction after large tumor resection is challenging. The free vascularized fibular graft (FVFG) offers the potential for rapid autograft incorporation as well as growing physeal transfer in pediatric patients. ... -
Vascularized Fibula-Based Physis Transfer: A Follow-Up Study of Longitudinal Bone Growth and Complications.
Shammas, Ronnie L; Avashia, Yash J; Farjat, Alfredo E; Catanzano, Anthony A; Levin, L Scott; Eward, William C; Brigman, Brian E; ... (8 authors) (Plastic and reconstructive surgery. Global open, 2017-05-25)<h4>Background</h4>The vascularized free fibula epiphyseal transfer provides an option for the preservation of limb lengthening after resection of the proximal humerus in pediatric sarcoma patients. The purpose of this study ...