Browsing by Author "Fan, Yang"
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Differential regulation of adhesion and phagocytosis of resting and activated microglia by dopamine
Fan, Yang; Chen, Zhilu; Pathak, Janak L; Carneiro, Ana MD; Chung, Chang Y (Frontiers in Cellular Neuroscience, 2018-09-11)© 2018 Fan, Chen, Pathak, Carneiro and Chung. Microglia, the immune competent cells of the central nervous system (CNS), normally exist in a resting state characterized by a ramified morphology with many processes, and become ... -
Mefenamic acid can attenuate depressive symptoms by suppressing microglia activation induced upon chronic stress.
Feng, Xiaoye; Fan, Yang; Chung, Chang Y (Brain research, 2020-08)BACKGROUND:Depression is the most debilitating neuropsychiatric disorder, and psychosocial stressors are major risk factors for the onset of depression. Depression is closely associated with chronic inflammation and microglia ... -
Signaling Pathways Controlling Microglia Chemotaxis.
Fan, Yang; Xie, Lirui; Chung, Chang Y (Molecules and cells, 2017-03-17)Microglia are the primary resident immune cells of the central nervous system (CNS). They are the first line of defense of the brain's innate immune response against infection, injury, and diseases. Microglia respond to ...