Browsing by Author "Fitzgerald, Michael C"

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Characterising phase variations in MALDI-TOF data and correcting them by peak alignment.

Lin, Simon M; Haney, Richard P; Campa, Michael J; Fitzgerald, Michael C; Patz, Edward F (Cancer Inform, 2005)

The use of MALDI-TOF mass spectrometry as a means of analyzing the proteome has been evaluated extensively in recent years. One of the limitations of this technique that has impeded the development of robust data analysis ...
Thermodynamic analysis of a molecular chaperone binding to unfolded protein substrates.

Xu, Ying; Schmitt, Sebastian; Tang, Liangjie; Jakob, Ursula; Fitzgerald, Michael C (Biochemistry, 2010-02-16)

Molecular chaperones are a highly diverse group of proteins that recognize and bind unfolded proteins to facilitate protein folding and prevent nonspecific protein aggregation. The mechanisms by which chaperones bind their ...