Now showing items 1-4 of 4

    • Genome-wide association study of Lp-PLA(2) activity and mass in the Framingham Heart Study. 

      Benjamin, Ashlee M; Gao, X; Ginsburg, Geoffrey Steven; Guyton, John Richard; McCarthy, Jeanette Joan; Milledge, Tom; Rivedal, D; ... (9 authors) (PLoS Genet, 2010-04-29)
      Lipoprotein-associated phospholipase A(2) (Lp-PLA(2)) is an emerging risk factor and therapeutic target for cardiovascular disease. The activity and mass of this enzyme are heritable traits, but major genetic determinants ...
    • Genome-wide association study of Lp-PLA(2) activity and mass in the Framingham Heart Study. 

      Benjamin, Ashlee M; Gao, X; Ginsburg, Geoffrey Steven; Guyton, John Richard; McCarthy, Jeanette Joan; Milledge, Tom; Rivedal, D; ... (9 authors) (PLoS Genet, 2010-04-29)
      Lipoprotein-associated phospholipase A(2) (Lp-PLA(2)) is an emerging risk factor and therapeutic target for cardiovascular disease. The activity and mass of this enzyme are heritable traits, but major genetic determinants ...
    • Host determinants of HIV-1 control in African Americans. 

      Carrington, Mary; Cronin, KD; Fellay, J; Gao, X; Ge, Dongliang; Goldstein, David Benjamin; Gumbs, Curtis E; ... (16 authors) (J Infect Dis, 2010-04-15)
      We performed a whole-genome association study of human immunodeficiency virus type 1 (HIV-1) set point among a cohort of African Americans (n = 515), and an intronic single-nucleotide polymorphism (SNP) in the HLA-B gene ...
    • Influence of HLA-C expression level on HIV control. 

      Apps, R; Bosch, R; Brumme, CJ; Brumme, ZL; Buchbinder, S; Carlson, JM; Carrington, Mary; ... (37 authors) (Science, 2013-04-05)
      A variant upstream of human leukocyte antigen C (HLA-C) shows the most significant genome-wide effect on HIV control in European Americans and is also associated with the level of HLA-C expression. We characterized ...