Now showing items 1-3 of 3

    • Human genetic and metabolite variation reveals that methylthioadenosine is a prognostic biomarker and an inflammatory regulator in sepsis 

      Wang, L; Ko, ER; Gilchrist, JJ; Pittman, KJ; Rautanen, A; Pirinen, M; Thompson, JW; ... (23 authors) (Science Advances, 2017-03-08)
      Sepsis is a deleterious inflammatory response to infection with high mortality. Reliable sepsis biomarkers could improve diagnosis, prognosis, and treatment. Integration of human genetics, patient metabolite and cytokine ...
    • Latent protein trees 

      Henao, R; Thompson, JW; Moseley, MA; Ginsburg, GS; Carin, L; Lucas, JE (Annals of Applied Statistics, 2013-06-01)
      Unbiased, label-free proteomics is becoming a powerful technique for measuring protein expression in almost any biological sample. The output of these measurements after preprocessing is a collection of features and their ...
    • Neuropeptide Y gene polymorphisms confer risk of early-onset atherosclerosis. 

      Shah, SH; Freedman, NJ; Zhang, L; Crosslin, DR; Stone, DH; Haynes, C; Johnson, J; ... (22 authors) (PLoS Genet, 2009-01)
      Neuropeptide Y (NPY) is a strong candidate gene for coronary artery disease (CAD). We have previously identified genetic linkage to familial CAD in the genomic region of NPY. We performed follow-up genetic, biostatistical, ...